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Anti-MCP-3/CCL7 Polyclonal Antibody is a Rabbit antibody targeting MCP-3/CCL7. Anti-MCP-3/CCL7 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $220 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Anti-MCP-3/CCL7 Polyclonal Antibody is a Rabbit antibody targeting MCP-3/CCL7. Anti-MCP-3/CCL7 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
Synonyms | Scya7, MCP-3, mcp3, marc, fic, chemokine (C-C motif) ligand 7 |
Ig Type | IgG |
Reactivity | Rat (predicted:Mouse) |
Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0); Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30 min; Antibody incubation with (MCP3) Polyclonal Antibody, Unconjugated (TMAB-01118) at 1:400 overnight at 4°C, followed by conjugation to the secondary antibody (labeled with HRP) and DAB staining. |
Application | |
Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Secreted. |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Research Background | This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008] |
Immunogen | KLH conjugated synthetic peptide: mouse MCP-3 |
Antigen Species | Mouse |
Gene Name | CCL7 |
Protein Name | C-C motif chemokine 7 |
Function | Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. |
Molecular Weight | Theoretical: 11 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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