GDNF Protein, Mouse, Recombinant

Name: GDNF Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPS-00039
Price: 138 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: HSCR3, HFB1-GDNF, Glial-Derived Neurotrophic Facto, ATF2, ATF-1) Copy Product Info

Synonyms: HSCR3, HFB1-GDNF, Glial-Derived Neurotrophic Facto, ATF2, ATF-1

Catalog No. TMPS-00039 Copy Product Info

GDNF Protein, Mouse, Recombinant is expressed in CHO Cells. The accession number is P48540.

Pack Size	Price	USA Stock	Global Stock
5 µg	$138	-	In Stock
10 µg	$216	-	In Stock
25 µg	$396	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as analyzed by SDS-PAGE > 95% as analyzed by HPLC

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 8.0 μg/ml, measured in a bioassay using C6 cells.
Description	GDNF Protein, Mouse, Recombinant is expressed in CHO Cells. The accession number is P48540.
Species	Mouse
Expression System	CHO Cells
Tag	Tag Free
Accession Number	P48540
Construction	Met77-Ile211
Protein Purity	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	HSCR3, HFB1-GDNF, Glial-Derived Neurotrophic Facto, ATF2, ATF-1
Research Background	Glial-Derived Neurotrophic Factor, also known as GDNF and ATF-1, is a neurotrophic factor belonging to the TGF-beta family. It is expressed in both central nervous system (CNS) and non-CNS tissues. GDNF signals through a receptor system composed of a RET and one of the four GFR alpha receptors. It promotes the survival and differentiation of dopaminergic neurons, and increases their high-affinity dopamine uptake. In a mouse Parkinson’s Disease model, GDNF has been shown to improve bradykinesia, rigidity, and postural instability. GDNF has also been shown to regulate kidney development, spermatogenesis and affect alcohol consumption.

Chemical Properties

Molecular Weight

17~22 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.