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Anti-CLEC7A Polyclonal Antibody (Synonyms: β-glucan receptor, Dectin-1, DECTIN1, DC-associated C-type lectin ...)
Catalog No. TMAB-00448 Copy Product Info
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Anti-CLEC7A Polyclonal Antibody is a Rabbit antibody targeting CLEC7A. Anti-CLEC7A Polyclonal Antibody can be used in WB.
Anti-CLEC7A Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-00448
Synonyms β-glucan receptor, Dectin-1, DECTIN1, DC-associated C-type lectin 1, CLECSF12, CD369, CANDF4, BGR, Beta-glucan receptor
Anti-CLEC7A Polyclonal Antibody is a Rabbit antibody targeting CLEC7A. Anti-CLEC7A Polyclonal Antibody can be used in WB.
Anti-CLEC7A Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CLEC7A Polyclonal Antibody is a Rabbit antibody targeting CLEC7A. Anti-CLEC7A Polyclonal Antibody can be used in WB. |
| Synonyms | β-glucan receptor, Dectin-1, DECTIN1, DC-associated C-type lectin 1, CLECSF12, CD369, CANDF4, BGR, Beta-glucan receptor |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Rat) |
| Verified Activity | Sample: Lane 1: Mouse Blood cell lysates Primary: Anti-CLEC7A (TMAB-00448) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 28 kDa Observed band size: 42,27,21 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Detected in dendritic cells, in paracortical and medullary regions of lymph nodes, and in spleen red pulp and white pulp. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq]. |
| Immunogen | KLH conjugated synthetic peptide: mouse CLEC7A |
| Antigen Species | Mouse |
| Gene Name | CLEC7A |
| Gene ID | |
| Protein Name | C-type lectin domain family 7 member A |
| Uniprot ID | |
| Biology Area | Macrophage / Inflamm. |
| Function | Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity). |
| Molecular Weight | Theoretical: 28 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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