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Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAP2K3 (Thr222). Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $218 | 7-10 days | |
100 μL | $317 | 7-10 days |
Description | Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAP2K3 (Thr222). Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA. |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Application | |
Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-300; ELISA: 1:5000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | mitogen-activated protein kinase kinase 3(MAP2K3) Homo sapiens The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008], |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human MAP2K3 around the phosphorylation site of Thr222. AA range:188-237 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Actual: 39 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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