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Serpin F2 Protein, Mouse, Recombinant (hFc)

Catalog No. TMPJ-00302
Synonyms: Alpha-2-PI, α-2-antiplasmin, Alpha-2-AP, α-2-AP, Serpinf2, Alpha-2-plasmin inhibitor, α-2-plasmin inhibitor, Alpha-2-antiplasmin, α-2-PI, Serpin F2

Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also express Serpin F2 mRNA at a moderate level indicated that it is a key regulator of plasmin-mediated proteolysis in these tissues.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Serpin F2 Protein, Mouse, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also express Serpin F2 mRNA at a moderate level indicated that it is a key regulator of plasmin-mediated proteolysis in these tissues.
Species Mouse
Expression System Human Cells
Tag C-Fc
Accession Number Q61247
Synonyms Alpha-2-PI, α-2-antiplasmin, Alpha-2-AP, α-2-AP, Serpinf2, Alpha-2-plasmin inhibitor, α-2-plasmin inhibitor, Alpha-2-antiplasmin, α-2-PI, Serpin F2
Amino Acid Val28-Lys491
Construction Recombinant Mouse Serine Protease Inhibitor-clade F2 is produced by our Mammalian expression system and the target gene encoding Val28-Lys491 is expressed with a human IgG1 Fc tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 90-120 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 8.0.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Research Background Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also express Serpin F2 mRNA at a moderate level indicated that it is a key regulator of plasmin-mediated proteolysis in these tissues.

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Keywords

Serpin F2 Protein, Mouse, Recombinant (hFc) a-2-PI a-2-antiplasmin Alpha-2-PI a-2-plasmin inhibitor α-2-antiplasmin Alpha-2-AP α-2-AP Serpinf2 Alpha-2-plasmin inhibitor α-2-plasmin inhibitor a-2-AP Alpha-2-antiplasmin α-2-PI Serpin F2 recombinant recombinant-proteins proteins protein

 

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