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Anti-EMMPRIN/CD147 Antibody-APC (1Z477)
🥰Excellent
Catalog No. TMAY-00420A
Anti-EMMPRIN/CD147 Antibody-APC (1Z477) is a APC-conjugated Mouse antibody targeting EMMPRIN/CD147. Anti-EMMPRIN/CD147 Antibody-APC (1Z477) can be used in FCM.
Anti-EMMPRIN/CD147 Antibody-APC (1Z477)
Anti-EMMPRIN/CD147 Antibody-APC (1Z477)
🥰Excellent
Catalog No. TMAY-00420A
Anti-EMMPRIN/CD147 Antibody-APC (1Z477) is a APC-conjugated Mouse antibody targeting EMMPRIN/CD147. Anti-EMMPRIN/CD147 Antibody-APC (1Z477) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-EMMPRIN/CD147 Antibody-APC (1Z477) is a APC-conjugated Mouse antibody targeting EMMPRIN/CD147. Anti-EMMPRIN/CD147 Antibody-APC (1Z477) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 1Z477 |
| Reactivity | Human |
| Verified Activity | Profile of anti-CD147 reactivity on HeLa cells analyzed by flow cytometry. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD147 / EMMPRIN (rh CD147 / EMMPRIN; NP_940991.1Met1-His205) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers. |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human CD147 / EMMPRIN protein |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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