Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CEP-11981 (ESK981; BOL 303213X) is an orally active tyrosine kinase inhibitor (TKI) that targets TIE2, VEGFR1-3, and FGFR1. It exhibits potential anti-tumor and anti-angiogenic effects.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 2,720.00 | |
50 mg | 10-14 weeks | $ 3,580.00 | |
100 mg | 10-14 weeks | $ 4,900.00 |
Description | CEP-11981 (ESK981; BOL 303213X) is an orally active tyrosine kinase inhibitor (TKI) that targets TIE2, VEGFR1-3, and FGFR1. It exhibits potential anti-tumor and anti-angiogenic effects. |
In vivo | Calcium channel-modulator-1 (20 mg/kg ; p.o.) causes a 35-37% decrease in systolic blood pressure in spontaneously hypertensive rats. However, iv administration of Calcium channel-modulator-1 to anesthetized spontaneously hypertensive rats causes a decrease in blood pressure.[1] |
Synonyms | BOL 303213X, ESK981 ; BOL 303213X, ESK981 |
Molecular Weight | 477.56 |
Formula | C28H27N7O |
CAS No. | 856691-93-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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CEP-11981 856691-93-5 ESK981 ; BOL 303213X BOL 303213X ESK981 ; BOL 303213X CEP11981 ESK-981 ESK981 BOL-303213X BOL303213X CEP 11981 ESK 981 inhibitor inhibit