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Anti-DR6 Polyclonal Antibody
😃Good
Catalog No. TMAB-00568
Alias tumor necrosis factor receptor superfamily, member 21
Anti-DR6 Polyclonal Antibody is a Rabbit antibody targeting DR6. Anti-DR6 Polyclonal Antibody can be used in WB.
Anti-DR6 Polyclonal Antibody
Anti-DR6 Polyclonal Antibody
😃Good
Catalog No. TMAB-00568Alias tumor necrosis factor receptor superfamily, member 21
Anti-DR6 Polyclonal Antibody is a Rabbit antibody targeting DR6. Anti-DR6 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-DR6 Polyclonal Antibody is a Rabbit antibody targeting DR6. Anti-DR6 Polyclonal Antibody can be used in WB. |
| Alias | tumor necrosis factor receptor superfamily, member 21 |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Chicken,Dog,Cow,Horse,Rabbit) |
| Verified Activity | 1. Sample: Heart (Mouse) Lysate at 40 μg Primary: Anti-DR6 (TMAB-00568) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52/68 kDa Observed band size: 52 kDa 2. Sample: Heart (Mouse) Lysate at 40 μg Primary: Anti-DR6 (TMAB-00568) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52/68 kDa Observed band size: 52 kDa |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein (Probable). |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | May activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). Tissue specificity: Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lower levels in lung, skeletal muscle, kidney, testis, uterus, small intestine, colon, spleen, bone marrow and fetal liver. Very low levels were found in adult liver and peripheral blood leukocytes. |
| Immunogen | KLH conjugated synthetic peptide: human DR6/CD358 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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