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Anti-DR6 Polyclonal Antibody (Alias: tumor necrosis factor receptor superfamily, member 21)
Catalog No. TMAB-00568 Copy Product Info
🥰Excellent
Anti-DR6 Polyclonal Antibody is a Rabbit antibody targeting DR6. Anti-DR6 Polyclonal Antibody can be used in WB.
Anti-DR6 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-00568
Alias tumor necrosis factor receptor superfamily, member 21
Anti-DR6 Polyclonal Antibody is a Rabbit antibody targeting DR6. Anti-DR6 Polyclonal Antibody can be used in WB.
Anti-DR6 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-DR6 Polyclonal Antibody is a Rabbit antibody targeting DR6. Anti-DR6 Polyclonal Antibody can be used in WB. |
| Synonyms | tumor necrosis factor receptor superfamily, member 21 |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Chicken,Dog,Cow,Horse,Rabbit) |
| Verified Activity | 1. Sample: Heart (Mouse) Lysate at 40 μg Primary: Anti-DR6 (TMAB-00568) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52/68 kDa Observed band size: 52 kDa 2. Sample: Heart (Mouse) Lysate at 40 μg Primary: Anti-DR6 (TMAB-00568) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52/68 kDa Observed band size: 52 kDa   |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein (Probable). |
| Tissue Specificity | Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lower levels in lung, skeletal muscle, kidney, testis, uterus, small intestine, colon, spleen, bone marrow and fetal liver. Very low levels were found in ad |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | May activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). Tissue specificity: Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lower levels in lung, skeletal muscle, kidney, testis, uterus, small intestine, colon, spleen, bone marrow and fetal liver. Very low levels were found in adult liver and peripheral blood leukocytes. |
| Immunogen | KLH conjugated synthetic peptide: human DR6/CD358 |
| Antigen Species | Human |
| Gene Name | TNFRSF21 |
| Gene ID | |
| Protein Name | Tumor necrosis factor receptor superfamily member 21 |
| Uniprot ID | |
| Function | May activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). |
| Molecular Weight | Theoretical: 52/68 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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