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polygalaxanthone III

Name: polygalaxanthone III
Brand: TargetMol
SKU: T3696
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T3696Cas No. 162857-78-5

Polygalaxanthone III can significantly inhibit chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.

polygalaxanthone III

🥰Excellent

Purity: 99.09%

Catalog No. T3696Cas No. 162857-78-5

Polygalaxanthone III can significantly inhibit chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.

Pack Size	Price	Availability
2 mg	$35	In Stock
5 mg	$54	In Stock
10 mg	$88	In Stock
25 mg	$166	In Stock
50 mg	$259	In Stock
100 mg	$386	In Stock

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Batch Information

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Purity:99.09%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

Polygalaxanthone III can significantly inhibit chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.

Chemical Properties

Molecular Weight	568.48
Formula	C₂₅H₂₈O₁₅
Cas No.	162857-78-5
Smiles	COc1cc2c(cc1O)oc1cc(O)c([C@@H]3O[C@H](CO[C@@H]4OC[C@](O)(CO)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)c(O)c1c2=O
Relative Density.	1.83 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (105.54 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7591 mL	8.7954 mL	17.5908 mL	87.9538 mL
5 mM	0.3518 mL	1.7591 mL	3.5182 mL	17.5908 mL
10 mM	0.1759 mL	0.8795 mL	1.7591 mL	8.7954 mL
20 mM	0.0880 mL	0.4398 mL	0.8795 mL	4.3977 mL
50 mM	0.0352 mL	0.1759 mL	0.3518 mL	1.7591 mL
100 mM	0.0176 mL	0.0880 mL	0.1759 mL	0.8795 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc