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Anti-PTPN11 Antibody (1T267)
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Catalog No. TMAC-03749
Alias SH-PTP 3, Shp2)
Anti-PTPN11 Antibody (1T267) is a Rabbit antibody targeting PTPN11. Anti-PTPN11 Antibody (1T267) can be used in ICC/IF,IHC,IP,WB.
Anti-PTPN11 Antibody (1T267)
Anti-PTPN11 Antibody (1T267)
😃Good
Catalog No. TMAC-03749Alias SH-PTP 3, Shp2)
Anti-PTPN11 Antibody (1T267) is a Rabbit antibody targeting PTPN11. Anti-PTPN11 Antibody (1T267) can be used in ICC/IF,IHC,IP,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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Chemical Properties
| Description | Anti-PTPN11 Antibody (1T267) is a Rabbit antibody targeting PTPN11. Anti-PTPN11 Antibody (1T267) can be used in ICC/IF,IHC,IP,WB. |
| Synonyms | SH-PTP 3, Shp2) |
| Ig Type | IgG |
| Clone | 1T267 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of SHP2 on different lysates using anti-SHP2 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: 293. 2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-SHP2 antibody. Counter stained with hematoxylin. 3. ICC staining SHP2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining SHP2 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining SHP2 in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.      |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non-transmembrane PTP, designated SH-PTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. SH2 domains generally mediate the association of regulatory molecules with specific phosphotyrosine-containing sites on autophosphorylated receptors, thereby controlling the initial interaction of receptors with these substrates. A second and much more widely expressed PTP with SH2 domains, SH-PTP2 (also designated PTP1D and Syp), has been identified. Strong sequence similarity between SH-PTP2 and the Drosophila gene corkscrew (CSW) and their similar patterns of expression suggest that SH-PTP2 is the human corkscrew homolog. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 70 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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