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HSPB8 Protein, Human, Recombinant (His)

Catalog No. TMPJ-01382
Synonyms: Small stress protein-like protein HSP22, CRYAC, E2IG1, Alpha-crystallin C chain, α-crystallin C chain, HspB8, Heat shock protein β-8, Protein kinase H11, HSP22, E2-induced gene 1 protein, Heat shock protein beta-8

Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity，appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
HSPB8 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,970.00
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Biological Description
Technical Params
Product Properties
Description Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity，appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Species Human
Expression System E. coli
Tag C-6His
Accession Number Q9UJY1
Synonyms Small stress protein-like protein HSP22, CRYAC, E2IG1, Alpha-crystallin C chain, α-crystallin C chain, HspB8, Heat shock protein β-8, Protein kinase H11, HSP22, E2-induced gene 1 protein, Heat shock protein beta-8
Amino Acid Met1-Thr196
Construction Recombinant Human Heat Shock Protein Beta-8 is produced by our E.coli expression system and the target gene encoding Met1-Thr196 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 23 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5mM EDTA, pH 7.4.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Research Background Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity，appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

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Keywords

HSPB8 Protein, Human, Recombinant (His) Small stress protein-like protein HSP22 CRYAC a-crystallin C chain E2IG1 Alpha-crystallin C chain α-crystallin C chain HspB8 Heat shock protein β-8 Protein kinase H11 HSP 22 Heat shock protein b-8 HSP22 E2-induced gene 1 protein HSP-22 Heat shock protein beta-8 recombinant recombinant-proteins proteins protein

 

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