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Ceftobiprole medocaril

Catalog No. T40475 CAS 376653-43-9

Synonyms: BAL5788

Ceftobiprole medocaril (BAL5788) is the parenteral prodrug of Ceftobiprole. Ceftobiprole is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Ceftobiprole medocaril Chemical Structure

Ceftobiprole medocaril, CAS 376653-43-9

Pack Size	Availability	Price/USD
1 mg	In stock	$ 195.00
5 mg	In stock	$ 437.00
10 mg	In stock	$ 646.00
25 mg	In stock	$ 987.00
50 mg	In stock	$ 1,380.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Ceftobiprole medocaril (BAL5788) is the parenteral prodrug of Ceftobiprole. Ceftobiprole is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA).
In vivo	Ceftobiprole medocaril (10, 40, 160 mg/kg; single dose; sc) has T 1/2 s from 20 min to 31 min, as the dose rose from 40 mg/kg to 160 mg/kg. The AUC/dose values for the escalating single doses ranges from 0.585 to 1.33, and the C max /dose values decreases from 1.08 to 0.90 in neutropenic thigh-infected mice [1]. The drug showed activities in the lung model similar to those in the thigh model.

Synonyms	BAL5788
Molecular Weight	690.66
Formula	C26H26N8O11S2
CAS No.	376653-43-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. W A Craig, et al. In vivo pharmacodynamics of ceftobiprole against multiple bacterial pathogens in murine thigh and lung infection models. Antimicrob Agents Chemother. 2008 Oct;52(10):3492-6.

Related compound libraries

This product is contained In the following compound libraries：

Pediatric Drug Library FDA-Approved & Pharmacopeia Drug Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ceftobiprole medocaril 376653-43-9 Microbiology/Virology Antibacterial Inhibitor BAL 5788 penicillin cephalosporin inhibit gram-positive pyrrolidinone MRSA Bacterial BAL5788 vancomycin pathogens staphylococci BAL-5788 gram-negative VRSA methicillin Prodrug inhibitor

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