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Cyclosporin C

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Catalog No. T19971Cas No. 59787-61-0
Alias Cyclosporin-C, Cs-C, CsC

Cyclosporin C (Cs-C) is a fungal metabolite against filamentous phytopathogenic fungi. Cyclosporin C has antifungal, antiviral, and immunosuppressant properties.

Cyclosporin C

Cyclosporin C

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Purity: 99.30%
Catalog No. T19971Alias Cyclosporin-C, Cs-C, CsCCas No. 59787-61-0
Cyclosporin C (Cs-C) is a fungal metabolite against filamentous phytopathogenic fungi. Cyclosporin C has antifungal, antiviral, and immunosuppressant properties.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$48-In Stock
5 mg$106-In Stock
10 mgPreferential-In Stock
25 mgPreferential-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.30%
Appearance:Solid
Color:White
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Product Introduction

Cyclosporin C AI Summary
Cyclosporin C exhibits notable in vitro binding affinity to Cyclophilin and demonstrates immunosuppressive activity, validated through a reporter gene assay (IL2_RGA) and mixed lymphocyte reaction in mice (MLR_M), with activity relative to Compound 1. The compound has an apparent permeability of 0.5 x 10^-6 cm/s in low-efflux MDCK2 cells at 2 µM and a thermodynamic aqueous solubility of 33,000 nM in pH 7.4 PBS. It also has a partition coefficient log D of 2.43 in 1,9-decadiene/aqueous buffer solution at pH 7.4. Additionally, its bioactivity related to permeability is confirmed by the PAMP assay, yielding a measured permeability of 2.8 x 10^-6 cm/s..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Cyclosporin C (Cs-C) is a fungal metabolite against filamentous phytopathogenic fungi. Cyclosporin C has antifungal, antiviral, and immunosuppressant properties.
SynonymsCyclosporin-C, Cs-C, CsC
Chemical Properties
Molecular Weight1218.61
FormulaC62H111N11O13
Cas No.59787-61-0
Smiles[H][C@]1(NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@@]([H])(NC(=O)[C@]([H])([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@]([H])(C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@]([H])(CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C1=O)[C@@H](C)O)C(C)C
Relative Density.1.033 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: Soluble

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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