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Scopolamine butylbromide

🥰Excellent
Catalog No. T2183Cas No. 149-64-4
Alias Hyoscine butylbromide, Butylscopolamine bromide, (-)-Scopolamine butylbromide

Scopolamine butylbromide ((-)-Scopolamine butylbromide) is a competitive antagonist of mAChR (IC50: 55.3 ± 4.3 nM).

Scopolamine butylbromide
Other Forms of Scopolamine butylbromide:

Scopolamine butylbromide

🥰Excellent
Purity: 99.95%
Catalog No. T2183Alias Hyoscine butylbromide, Butylscopolamine bromide, (-)-Scopolamine butylbromideCas No. 149-64-4
Scopolamine butylbromide ((-)-Scopolamine butylbromide) is a competitive antagonist of mAChR (IC50: 55.3 ± 4.3 nM).
Pack SizePriceAvailabilityQuantity
200 mg$29In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:99.95%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Scopolamine butylbromide ((-)-Scopolamine butylbromide) is a competitive antagonist of mAChR (IC50: 55.3 ± 4.3 nM).
Targets&IC50
mAChR:55.3 ± 4.3 nM
SynonymsHyoscine butylbromide, Butylscopolamine bromide, (-)-Scopolamine butylbromide
Chemical Properties
Molecular Weight440.37
FormulaC21H30NO4·Br
Cas No.149-64-4
Smiles[Br-].CCCC[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1
Relative Density.no data available
ColorWhite
Appearancesolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (181.67 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2708 mL11.3541 mL22.7082 mL113.5409 mL
5 mM0.4542 mL2.2708 mL4.5416 mL22.7082 mL
10 mM0.2271 mL1.1354 mL2.2708 mL11.3541 mL
20 mM0.1135 mL0.5677 mL1.1354 mL5.6770 mL
50 mM0.0454 mL0.2271 mL0.4542 mL2.2708 mL
100 mM0.0227 mL0.1135 mL0.2271 mL1.1354 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Keywords

Scopolamine butylbromideMuscarinic acetylcholine receptormAChRInhibitorinhibitButylscopolamine BromideButylscopolamine
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