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Potent EGFR-kinase inhibitor (IC50 = 0.7 nM). Displays >3000-fold selectivity against a panel of serine/threonine kinases. Reduces metastasis and angiogenesis in a mouse model of pancreatic cancer. Antihypertensive and orally bioavailable.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | TBD | 35 days |
Description | Potent EGFR-kinase inhibitor (IC50 = 0.7 nM). Displays >3000-fold selectivity against a panel of serine/threonine kinases. Reduces metastasis and angiogenesis in a mouse model of pancreatic cancer. Antihypertensive and orally bioavailable. |
Targets&IC50 | EGFR tyrosine kinase:0.7 nM (IC50) |
Molecular Weight | 366.85 |
Formula | C20H19ClN4O |
Cas No. | 2230253-82-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO: Soluble |
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