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Anti-Clusterin Antibody (8V482)

😃Good
Catalog No. TMAY-01837
Alias TRPM-2, TRPM2, SP-40, SGP-2, SGP2, NA1/NA2, KUB1, clusterin, CLU2, CLU1, CLI, APO-J, APOJ, AAG4

Anti-Clusterin Antibody (8V482) is a Rabbit antibody targeting Clusterin. Anti-Clusterin Antibody (8V482) can be used in IHC-P.

Anti-Clusterin Antibody (8V482)

Anti-Clusterin Antibody (8V482)

😃Good
Catalog No. TMAY-01837Alias TRPM-2, TRPM2, SP-40, SGP-2, SGP2, NA1/NA2, KUB1, clusterin, CLU2, CLU1, CLI, APO-J, APOJ, AAG4
Anti-Clusterin Antibody (8V482) is a Rabbit antibody targeting Clusterin. Anti-Clusterin Antibody (8V482) can be used in IHC-P.
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100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Clusterin Antibody (8V482) is a Rabbit antibody targeting Clusterin. Anti-Clusterin Antibody (8V482) can be used in IHC-P.
AliasTRPM-2, TRPM2, SP-40, SGP-2, SGP2, NA1/NA2, KUB1, clusterin, CLU2, CLU1, CLI, APO-J, APOJ, AAG4
Ig Type
Monoclonal Rabbit IgG
Clone
8V482
Reactivity
Human
Verified Activity
1. Immunochemical staining of human CLU in human pancreas with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

2. Immunochemical staining of human CLU in human ovarian cancer with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

3. Immunochemical staining of human CLU in human appendix with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Application
IHC-P
Recommended Dose
IHC-P: 1:100-1:500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Clusterin / Apolipoprotein J / Apo-J / CLU (rh Clusterin / Apolipoprotein J / Apo-J / CLU; TMPY-01691; NP_001822.2; Met1-Glu501).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundClusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Clusterin / Apolipoprotein J / Apo-J / CLU protein (TMPY-01691)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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