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Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl-

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Catalog No. T60056Cas No. 936345-34-5

Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl- is a progesterone receptor antagonist with antiprogestin effects.

Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl-

Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl-

🥰Excellent
Purity: 99.71%
Catalog No. T60056Cas No. 936345-34-5
Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl- is a progesterone receptor antagonist with antiprogestin effects.
Pack SizePriceAvailabilityQuantity
1 mg$117In Stock
5 mg$262In Stock
10 mg$387In Stock
25 mg$592In Stock
50 mg$828In Stock
100 mg$1,110In Stock
500 mg$2,230In Stock
1 mL x 10 mM (in DMSO)$277In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:99.71%
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Product Introduction

Bioactivity
Description
Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl- is a progesterone receptor antagonist with antiprogestin effects.
Chemical Properties
Molecular Weight359.44
FormulaC18H21N3O3S
Cas No.936345-34-5
SmilesO(C1=C(N(CS(C)(=O)=O)N=C1C)C2CC2)C3=CC(C)=C(C#N)C(C)=C3
Relative Density.1.31 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mg/mL (27.82 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7821 mL13.9105 mL27.8211 mL139.1053 mL
5 mM0.5564 mL2.7821 mL5.5642 mL27.8211 mL
10 mM0.2782 mL1.3911 mL2.7821 mL13.9105 mL
20 mM0.1391 mL0.6955 mL1.3911 mL6.9553 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

ProgesteroneReceptorProgesterone Receptorprogesterone receptorBenzonitrile, 4[[5cyclopropyl3methyl1[(methylsulfonyl)methyl]1Hpyrazol4yl]oxy]2,6dimethylBenzonitrile, 4 [[5 cyclopropyl 3 methyl 1 [(methylsulfonyl)methyl] 1H pyrazol 4 yl]oxy] 2,6 dimethyl
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