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Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody

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Catalog No. TMAC-03419

Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Presenilin 2 (Ser330). Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.

Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody

Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody

😃Good
Catalog No. TMAC-03419
Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Presenilin 2 (Ser330). Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Presenilin 2 (Ser330). Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-300; ELISA: 1:5000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research Backgroundpresenilin 2(PSEN2) Homo sapiens Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified. [provided by RefSeq, Jul 2008],
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human Presenilin 2 around the phosphorylation site of Ser330. AA range:296-345
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 50 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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