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Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody
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Catalog No. TMAC-03419
Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Presenilin 2 (Ser330). Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.
Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody
Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody
😃Good
Catalog No. TMAC-03419
Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Presenilin 2 (Ser330). Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $216 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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Chemical Properties
| Description | Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Presenilin 2 (Ser330). Anti-Phospho-Presenilin 2 (Ser330) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-300; ELISA: 1:5000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Appearance | Liquid |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research Background | presenilin 2(PSEN2) Homo sapiens Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified. [provided by RefSeq, Jul 2008], |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human Presenilin 2 around the phosphorylation site of Ser330. AA range:296-345 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 50 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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