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Synonyms: TRNR1, RETL1, RET1L, GFR-α-1, GFR-ALPHA-1, GFR α-1/GFRA1, GDNFRA, GDNFR, GDNF family receptor α1, GDNF family receptor alpha 1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-GFR Alpha-1/GFRA1 Polyclonal Antibody is a Rabbit antibody targeting GFR Alpha-1/GFRA1. Anti-GFR Alpha-1/GFRA1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | TRNR1, RETL1, RET1L, GFR-α-1, GFR-ALPHA-1, GFR α-1/GFRA1, GDNFRA, GDNFR, GDNF family receptor α1, GDNF family receptor alpha 1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq] |
| Immunogen | KLH conjugated synthetic peptide: human GFR Alpha-1 |
| Antigen Species | Human |
| Gene Name | GFRA1 |
| Gene ID | |
| Protein Name | GDNF family receptor alpha-1 |
| Uniprot ID | |
| Biology Area | Neurotrophins |
| Function | Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. |
| Molecular Weight | Theoretical: 44 kDa. Actual: 47 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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