Shopping Cart
Remove All
Your shopping cart is currently empty
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His)
(Synonyms: α-chain, FCRN, Fc fragment of IgG, receptor, transporter, α, Fc fragment of IgG, receptor, transporter, alpha, alpha-chain) Copy Product InfoSynonyms: α-chain, FCRN, Fc fragment of IgG, receptor, transporter, α, Fc fragment of IgG, receptor, transporter, alpha, alpha-chain
Catalog No. TMPY-02082 Copy Product Info
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.5 kDa and the accession number is P55899-1&P61769.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $57 | - | In Stock | |
| 10 µg | $89 | - | In Stock | |
| 20 µg | $145 | - | In Stock | |
| 50 µg | $282 | 7-10 days | 7-10 days | |
| 100 µg | $473 | - | In Stock | |
| 200 µg | $833 | 7-10 days | 7-10 days | |
| 500 µg | $1,760 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
Select Batch
Purity:SDS-PAGE: 96%; SEC-HPLC: 90.9%
Appearance:Lyophilized powder
Color:White
Contact us for more batch information
Resource Download
Product Information
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | 1. Measured by its ability to bind human IgG1 in a functional ELISA. 2. Loaded Human FcRn recombinant protein on His1K Biosensor, can bind IgG1 with an affinity constant of 0.11 µM as determined in a BLI assay. 3. Loaded Human FcRn recombinant protein on His1k Biosensor, can bind IgG4 Fc with an affinity constant of 0.08 µM as determined in a BLI assay. 4. Captured Human FcRn recombinant protein on Anti-His Chip can bind Bevacizumab (IgG1) with an affinity constant of 0.11 µM as determined in an SPR assay (Biacore T200). 5. Captured Human FcRn recombinant protein on Anti-His Chip can bind Nivolumab (IgG4) with an affinity constant of 0.23 µM as determined in an SPR assay (Biacore T200). 6. The purity of Human FCGRT & B2M Heterodimer Protein is more than 90% and the molecular weight of this protein is around 45-53 kDa verified by SEC-MALS. 7. Loaded Recombinant Human FCGRT & B2M Heterodimer Protein, His Tag on His1K Biosensor, can bind Anti-Erbb2 Antibody, human IgG1 with an affinity constant of 11.1nM as determined in BLI assay (QC tested). |
| Description | FCGRT & B2M Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.5 kDa and the accession number is P55899-1&P61769. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | P55899-1&P61769 |
| Construction | A DNA sequence encoding the extracellular domain (Met1-Ser297) of human FCGRT (P55899-1) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the human B2M (P61769) (Met1-Met119) constructed the plasmid 2. The two plasmids were co-expressed and the FCGRT / B2M heterodimer was purified. Predicted N terminal: Ala 24 & Ile 21 |
| Protein Purity | > 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-HPLC  , |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | α-chain, FCRN, Fc fragment of IgG, receptor, transporter, α, Fc fragment of IgG, receptor, transporter, alpha, alpha-chain |
| Molecular Weight | 43.5 kDa (predicted); 35 & 12 kDa (reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Calculator
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Recombinant Proteins
Keywords
Preview
Related Tags: FCGRT & B2M Heterodimer Protein, Human, Recombinant (His) chemical structure | FCGRT & B2M Heterodimer Protein, Human, Recombinant (His) molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.