PSP Protein, Human, Recombinant (His)

Name: PSP Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-01057
Rating: 4.5 (1 reviews)

(Synonyms: PSPH, PSPase, PSP, Phosphoserine Phosphatase, O-Phosphoserine Phosphohydrolase, L-3-Phosphoserine Phosphatase) Copy Product Info

Synonyms: PSPH, PSPase, PSP, Phosphoserine Phosphatase, O-Phosphoserine Phosphohydrolase, L-3-Phosphoserine Phosphatase

Catalog No. TMPJ-01057 Copy Product Info

Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.

Pack Size	Price	USA Stock	Global Stock
10 µg	$129	7-10 days	7-10 days
20 µg	$198	7-10 days	7-10 days
50 µg	$390	7-10 days	7-10 days
100 µg	$626	7-10 days	7-10 days
200 µg	$987	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.
Species	Human
Expression System	E. coli
Tag	C-6xHis
Accession Number	P78330
Amino Acid	Met1-Glu225
Construction	Met1-Glu225
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 4M Urea, 5 mM EDTA, pH 8.0.
Synonyms	PSPH, PSPase, PSP, Phosphoserine Phosphatase, O-Phosphoserine Phosphohydrolase, L-3-Phosphoserine Phosphatase
Research Background	Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.

Chemical Properties

Molecular Weight

25-30 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.