Phytohemagglutinin P

Name: Phytohemagglutinin P
Brand: TargetMol
SKU: T78491
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: PHA-P, PHAP) Copy Product Info

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Synonyms: PHA-P, PHAP

Catalog No. T78491 Copy Product Info

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Phytohemagglutinin P (PHA-P) is a naturally occurring lectin, the protein form of PHA.PHA is a selective T-cell mitogen that binds T-cell receptors and enhances HIV-1 replication.

Phytohemagglutinin P

Pack Size	Price	USA Stock	Global Stock	Quantity
2 mg	$29	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid

Color:White

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Product Introduction

Bioactivity

Description	Phytohemagglutinin P (PHA-P) is a naturally occurring lectin, the protein form of PHA.PHA is a selective T-cell mitogen that binds T-cell receptors and enhances HIV-1 replication.
In vitro	Phytohemagglutinin P (1-10 μg/mL) significantly stimulated PBMC proliferation and induced the expression of multiple cytokines (e.g., IL-2, IFN-γ). Phytohemagglutinin P activity is concentration-dependent and effectively initiates T cell-mediated immune responses[1].
In vivo	Phytohemagglutinin-P, administered intraperitoneally at doses of 25 and 50 mg/kg daily for 15 days to male Sprague-Dawley rats, resulted in a reduction of longitudinal bone growth, chondrocyte numbers, cartilage plate thickness, metaphyseal hard tissue mass, calcified cartilage core percentage, and osteoblast count per millimeter of bone surface. Furthermore, PHA-P elevated osteoclast quantity, osteoclastic nuclei labeling, and the average nuclei count per osteoclast [1].
Synonyms	PHA-P, PHAP

Storage & Solubility Information

Storage	Keep away from direct sunlight Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	H2O: 5 mg/mL, Sonication is recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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