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SNIPERs

Specific and nongenetic IAP-based protein erasers (SNIPERs) are hybrid molecules that designed based on IAPs, and used to degrade the target proteins closely associated with diseases. Their structures consist of three parts, including target protein ligand, E3 ligase ligand and the linker between them. SNIPERs (PROTACs) degrade diseases-associated proteins through human inherent ubiquitin-proteasome system. So far, many SNIPERs have been developed to treat diseases that difficult to handle by traditional methods, such as radiotherapy, chemotherapy and small molecule inhibitors, and showed promising prospects in application.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T81141 SNIPER(TACC3)-2 hydrochloride 98%
SNIPER(TACC3)-2 hydrochloride
SNIPER(TACC3)-2 hydrochloride is a compound that induces degradation of the TACC3 protein through the ubiquitin-proteasome pathway by exploiting an IAP ligand, l...
T81142 SNIPER(TACC3)-1 hydrochloride 98%
SNIPER(TACC3)-1 hydrochloride
SNIPERTACC3-1 hydrochloride, an IAP ligand-based compound, selectively degrades the TACC3 protein through the ubiquitin-proteasome pathway, thereby inducing canc...
SNIPER(TACC3)-2 hydrochloride
T81141
SNIPER(TACC3)-2 hydrochloride is a compound that induces degradation of the TACC3 protein through the ubiquitin-proteasome pathway by exploiting an IAP ligand, l...
SNIPER(TACC3)-1 hydrochloride
T81142
SNIPERTACC3-1 hydrochloride, an IAP ligand-based compound, selectively degrades the TACC3 protein through the ubiquitin-proteasome pathway, thereby inducing canc...
TargetMol