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Anti-Phospho-SLP-76 (Tyr145) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SLP-76 (Tyr145). Anti-Phospho-SLP-76 (Tyr145) Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $218 | 7-10 days | |
100 μL | $318 | 7-10 days |
Description | Anti-Phospho-SLP-76 (Tyr145) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SLP-76 (Tyr145). Anti-Phospho-SLP-76 (Tyr145) Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
Reactivity | Human,Mouse |
Application | |
Recommended Dose | WB: 1:1000-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | lymphocyte cytosolic protein 2(LCP2) Homo sapiens SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T c |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human SLP-76 around the phosphorylation site of Tyr145 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Actual: 75 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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