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PFB-FDGlu

Name: PFB-FDGlu
Brand: TargetMol
SKU: T39518
Price: 152 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T39518Cas No. 209540-62-5

PFB-FDGlu is a lysosomal Glucocerebrosidase (GCase) substrate with cell-permeable specificity that is cleaved to produce fluorescein.PFB-FDGlu is often used in conjunction with a flow cytometer to measure GCase activity in living cells on an individual cell basis.

PFB-FDGlu

🥰Excellent

Purity: 99.86%

Catalog No. T39518Cas No. 209540-62-5

Pack Size	Price	Availability
1 mg	$152	In Stock
5 mg	$373	In Stock
10 mg	$556	In Stock
25 mg	$896	In Stock
50 mg	$1,220	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.86%

ee:100%

Resource Download

COA CSFC FNMR ORP LCMS HNMR

Product Introduction

Bioactivity

Description	PFB-FDGlu is a lysosomal Glucocerebrosidase (GCase) substrate with cell-permeable specificity that is cleaved to produce fluorescein.PFB-FDGlu is often used in conjunction with a flow cytometer to measure GCase activity in living cells on an individual cell basis.
In vitro	Cell-permeable PFB-FDGlu can be utilized with a flow cytometer to measure GCase activity in living cells on a single-cell basis[1].

Chemical Properties

Molecular Weight	865.66
Formula	C₃₉H₃₂F₅NO₁₆
Cas No.	209540-62-5
Smiles	O=C1OC2(C=3C1=CC(NC(=O)C4=C(F)C(F)=C(F)C(F)=C4F)=CC3)C=5C(OC=6C2=CC=C(O[C@H]7[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O7)C6)=CC(O[C@H]8[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O8)=CC5
Relative Density.	1.82 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 252.5 mg/mL (291.68 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.1552 mL	5.7759 mL	11.5519 mL	57.7594 mL
5 mM	0.2310 mL	1.1552 mL	2.3104 mL	11.5519 mL
10 mM	0.1155 mL	0.5776 mL	1.1552 mL	5.7759 mL
20 mM	0.0578 mL	0.2888 mL	0.5776 mL	2.8880 mL
50 mM	0.0231 mL	0.1155 mL	0.2310 mL	1.1552 mL
100 mM	0.0116 mL	0.0578 mL	0.1155 mL	0.5776 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc