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Ergosterol peroxide

Name: Ergosterol peroxide
Brand: TargetMol
SKU: TMA1743
Price: 107 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TMA1743Cas No. 2061-64-5

Alias NSC31324, NSC 31324

Ergosterol peroxide (NSC 31324) is a derivative from mushrooms with anti-tumor, pro-apoptotic anti-mycobacterial and anti-proliferative activities.Ergosterol peroxide has anti-inflammatory and antioxidant activities and is toxic to parasites.

Ergosterol peroxide

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Purity: 98.43%

Catalog No. TMA1743Alias NSC31324, NSC 31324Cas No. 2061-64-5

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$107	-	In Stock
5 mg	$235	-	In Stock
10 mg	$372	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.43%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Ergosterol peroxide (NSC 31324) is a derivative from mushrooms with anti-tumor, pro-apoptotic anti-mycobacterial and anti-proliferative activities.Ergosterol peroxide has anti-inflammatory and antioxidant activities and is toxic to parasites.
Targets&IC50	T. cruzi:6.74 µg/mL
In vitro	Ergosterol peroxide showed an IC50 of 6.74 µg/mL against T. cruzi, but did not lyse erythrocytes even at concentrations as high as 1600 µg/mL and had no toxic effects on mammalian cells. In vitro experiments showed that Ergosterol peroxide exhibited significant lysogenic activity when interacting with Trypanosoma cruzi, possibly due to rupture of the parasite cell membrane. [1]
Synonyms	NSC31324, NSC 31324

Chemical Properties

Molecular Weight	428.65
Formula	C₂₈H₄₄O₃
Cas No.	2061-64-5
Smiles	C[C@@]12[C@@]3([C@@]4([C@]5([C@](C)(CC3)[C@@]([C@@H](/C=C/[C@@H](C(C)C)C)C)(CC5)[H])[H])C=C[C@@]1(OO4)C[C@@H](O)CC2)[H]
Relative Density.	1.08g/cm3

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Methanol: 12.5 mg/mL (29.16 mM), Sonication is recommended.

DMSO: 3.12 mg/mL (7.28 mM), Sonication is recommended.

Solution Preparation Table

DMSO/Methanol

	1mg	5mg	10mg	50mg
1 mM	2.3329 mL	11.6645 mL	23.3291 mL	116.6453 mL
5 mM	0.4666 mL	2.3329 mL	4.6658 mL	23.3291 mL

Methanol

	1mg	5mg	10mg	50mg
10 mM	0.2333 mL	1.1665 mL	2.3329 mL	11.6645 mL
20 mM	0.1166 mL	0.5832 mL	1.1665 mL	5.8323 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc