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CXCL7 Protein, Cynomolgus, Recombinant (mFc)
Catalog No. TMPY-03043 Copy Product Info
CXCL7 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34.3 kDa and the accession number is F6SCP6.
CXCL7 Protein, Cynomolgus, Recombinant (mFc)
Catalog No. TMPY-03043
Copy Product InfoCXCL7 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34.3 kDa and the accession number is F6SCP6.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $73 | 7-10 days | 7-10 days | |
| 10 μg | $118 | 7-10 days | 7-10 days | |
| 20 μg | $196 | 7-10 days | 7-10 days | |
| 50 μg | $443 | 7-10 days | 7-10 days |
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Biological Activity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | CXCL7 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34.3 kDa and the accession number is F6SCP6. |
| Species | Cynomolgus |
| Expression System | HEK293 Cells |
| Tag | N-mFc |
| Accession Number | F6SCP6 |
| Synonyms | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| Construction | A DNA sequence encoding the cynomolgus PPBP (F6SCP6) (Thr59-Asp128) was expressed fused with the Fc region of mouse IgG1 at the N-terminus. Predicted N terminal: Asp |
| Protein Purity | > 90 % as determined by SDS-PAGE |
| Molecular Weight | 34.3 kDa (predicted); 38 kDa (reducing conditions) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Research Background | Pro-platelet basic protein (PPBP) is also known as Chemokine (C-X-C motif) ligand 7 (CXCL7) and nucleosome assembly protein (Nap-2). Nap-2 / PPBP / CXCL7 is released in large amounts from platelets following their activation and is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. Nap-2 / PPBP / CXCL7 has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Nap-2 is a ligand for CXCR1 and CXCR2, and Nap-2, Nap-2 (73), Nap-2 (74), Nap-2 (1-66), and most potent Nap-2 (1-63) are chemoattractants and activators for neutrophils.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
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