TNF alpha Protein, Rabbit, Recombinant

Name: TNF alpha Protein, Rabbit, Recombinant
Brand: TargetMol
SKU: TMPJ-00779
Price: 58 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Tumor Necrosis Factor Ligand Superfamily Member 2, Tumor Necrosis Factor, TNF-α, TNFSF2, TNF-Alpha, TNF-a, TNFA, TNF α, TNF, Cachectin) Copy Product Info

Synonyms: Tumor Necrosis Factor Ligand Superfamily Member 2, Tumor Necrosis Factor, TNF-α, TNFSF2, TNF-Alpha, TNF-a, TNFA, TNF α, TNF, Cachectin

Catalog No. TMPJ-00779 Copy Product Info

Purity: 98%

Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.

Pack Size	Price	USA Stock	Global Stock
5 µg	$58	-	In Stock
10 µg	$92	-	In Stock
20 µg	$148	7-10 days	7-10 days
50 µg	$278	7-10 days	7-10 days
100 µg	$436	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:98%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
Species	Rabbit
Expression System	E. coli
Tag	Tag Free
Accession Number	P04924
Amino Acid	Val78-Leu235
Construction	Val78-Leu235
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 250 mM NaCl, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Tumor Necrosis Factor Ligand Superfamily Member 2, Tumor Necrosis Factor, TNF-α, TNFSF2, TNF-Alpha, TNF-a, TNFA, TNF α, TNF, Cachectin
Research Background	Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.

Chemical Properties

Molecular Weight

18 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.