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TNF alpha Protein, Rabbit, Recombinant

Catalog No. TMPJ-00779
Synonyms: TNF-a, Tumor Necrosis Factor, TNF-α, TNF α, Cachectin, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF, TNFA, TNF-Alpha, TNFSF2

Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
TNF alpha Protein, Rabbit, Recombinant
Pack Size Availability Price/USD Quantity
10 μg In stock $ 92.00
20 μg 5 days $ 148.00
50 μg 5 days $ 278.00
100 μg 5 days $ 436.00
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Biological Description
Technical Params
Product Properties
Description Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
Species Rabbit
Expression System E. coli
Tag None
Accession Number P04924
Synonyms TNF-a, Tumor Necrosis Factor, TNF-α, TNF α, Cachectin, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF, TNFA, TNF-Alpha, TNFSF2
Amino Acid Val78-Leu235
Construction Recombinant Rabbit Tumor Necrosis Factor Alpha is produced by our E.coli expression system and the target gene encoding Val78-Leu235 is expressed.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)

Molecular Weight 18 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.

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Keywords

TNF alpha Protein, Rabbit, Recombinant TNF-a Tumor Necrosis Factor TNF-α TNFSF 2 TNF α Cachectin Tumor Necrosis Factor Ligand Superfamily Member 2 TNF TNFSF-2 TNFA TNF-Alpha TNFSF2 recombinant recombinant-proteins proteins protein

 

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