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TNF alpha Protein, Rabbit, Recombinant

(Synonyms: Tumor Necrosis Factor Ligand Superfamily Member 2, Tumor Necrosis Factor, TNF-α, TNFSF2, TNF-Alpha, TNF-a, TNFA, TNF α, TNF, Cachectin) Copy Product Info

Synonyms: Tumor Necrosis Factor Ligand Superfamily Member 2, Tumor Necrosis Factor, TNF-α, TNFSF2, TNF-Alpha, TNF-a, TNFA, TNF α, TNF, Cachectin

Catalog No. TMPJ-00779 Copy Product Info
Purity: 98%
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.

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Purity:98%
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Description
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
Species
Rabbit
Expression System
E. coli
TagTag Free
Accession NumberP04924
Amino AcidVal78-Leu235
ConstructionVal78-Leu235
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
https://cdn.targetmol.com/group3/M00/12/EB/CgoaEGZG0yqEJ8aqAAAAALuXH-o183.png
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 250 mM NaCl, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsTumor Necrosis Factor Ligand Superfamily Member 2, Tumor Necrosis Factor, TNF-α, TNFSF2, TNF-Alpha, TNF-a, TNFA, TNF α, TNF, Cachectin
Research Background
Chemical Properties
Molecular Weight18 KDa (reducing condition)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: TNF alpha Protein, Rabbit, Recombinant chemical structure | TNF alpha Protein, Rabbit, Recombinant molecular weight