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Anti-Prothrombin Polyclonal Antibody
(Synonyms: Prothrombin, F2, Coagulation factor II) Copy Product Info
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Synonyms: Prothrombin, F2, Coagulation factor II
Catalog No. TMAB-01583 Copy Product Info
🥰Excellent
Anti-Prothrombin Polyclonal Antibody is a Rabbit antibody targeting Prothrombin. Anti-Prothrombin Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.
Anti-Prothrombin Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Prothrombin Polyclonal Antibody is a Rabbit antibody targeting Prothrombin. Anti-Prothrombin Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Prothrombin, F2, Coagulation factor II |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1ug/test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space. |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Des-gamma carboxyprothrombin (DCP), also known as protein induced by vitamin K absence/antagonist-II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin. Normally, the prothrombin precursor undergoes post-translational carboxylation (addition of a carboxylic acid group) by gamma-glutamyl carboxylase in the liver prior to secretion into plasma. DCP/PIVKA-II may be detected in people with deficiency of vitamin K (due to poor nutrition or malabsorption) and in those taking warfarin or other medication that inhibits the action of vitamin K. |
| Immunogen | KLH conjugated synthetic peptide: human Prothrombin |
| Antigen Species | Human |
| Gene Name | F2 |
| Gene ID | |
| Protein Name | Prothrombin |
| Uniprot ID | |
| Biology Area | Common |
| Function | Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. |
| Molecular Weight | Theoretical: 70 kDa. Actual: 70-75 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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