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Anti-PCSK9 Antibody (5M140)

😃Good
Catalog No. TMAY-01002
Alias proprotein convertase subtilisin/kexin type 9, PC9, NARC-1, NARC1, LDLCQ1, HCHOLA3, FH3

Anti-PCSK9 Antibody (5M140) is a Mouse antibody targeting PCSK9. Anti-PCSK9 Antibody (5M140) can be used in ELISA(Cap).

Anti-PCSK9 Antibody (5M140)

Anti-PCSK9 Antibody (5M140)

😃Good
Catalog No. TMAY-01002Alias proprotein convertase subtilisin/kexin type 9, PC9, NARC-1, NARC1, LDLCQ1, HCHOLA3, FH3
Anti-PCSK9 Antibody (5M140) is a Mouse antibody targeting PCSK9. Anti-PCSK9 Antibody (5M140) can be used in ELISA(Cap).
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-PCSK9 Antibody (5M140) is a Mouse antibody targeting PCSK9. Anti-PCSK9 Antibody (5M140) can be used in ELISA(Cap).
Aliasproprotein convertase subtilisin/kexin type 9, PC9, NARC-1, NARC1, LDLCQ1, HCHOLA3, FH3
Ig Type
Monoclonal Mouse IgG1
Clone
5M140
Reactivity
Human
Application
ELISA(Cap)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PCSK9 (rh PCSK9; AAV67948.1Met1-Gln692). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundProprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human PCSK9 Protein
Antigen Species
Human
Biology Area
Serine Proteases and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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