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Anti-Erythropoietin Antibody (3V254)

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Catalog No. TMAY-03548

Anti-Erythropoietin Antibody (3V254) is a Rabbit antibody targeting Erythropoietin. Anti-Erythropoietin Antibody (3V254) can be used in IHC-P.

Anti-Erythropoietin Antibody (3V254)

Anti-Erythropoietin Antibody (3V254)

😃Good
Catalog No. TMAY-03548
Anti-Erythropoietin Antibody (3V254) is a Rabbit antibody targeting Erythropoietin. Anti-Erythropoietin Antibody (3V254) can be used in IHC-P.
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100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Erythropoietin Antibody (3V254) is a Rabbit antibody targeting Erythropoietin. Anti-Erythropoietin Antibody (3V254) can be used in IHC-P.
Ig Type
Monoclonal Rabbit IgG
Clone
3V254
Reactivity
Mouse
Verified Activity
1. Immunochemical staining of Mouse Erythropoietin in Mouse kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.

2. Immunochemical staining of Mouse Erythropoietin in Mouse liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Application
IHC-P
Recommended Dose
IHC-P: 1:50-1:200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse Erythropoietin (rM Erythropoietin; TMPY-00443; NP_031968.1; Met1-Arg192).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundErythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. It also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. Genetic variation in erythropoietin is associated with susceptbility to microvascular complications of diabetes type 2. These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. It has a longer circulating half-life in vivo. Erythropoietin is being much misused as a performance-enhancing drug in endurance athletes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse Erythropoietin Protein (TMPY-00443)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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