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Anti-ABCB1 Antibody (8E719)
😃Good
Catalog No. TMAC-02513
Alias PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20
Anti-ABCB1 Antibody (8E719) is a Mouse antibody targeting ABCB1. Anti-ABCB1 Antibody (8E719) can be used in WB,IP,IF.
Anti-ABCB1 Antibody (8E719)
Anti-ABCB1 Antibody (8E719)
😃Good
Catalog No. TMAC-02513Alias PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20
Anti-ABCB1 Antibody (8E719) is a Mouse antibody targeting ABCB1. Anti-ABCB1 Antibody (8E719) can be used in WB,IP,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $427 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-ABCB1 Antibody (8E719) is a Mouse antibody targeting ABCB1. Anti-ABCB1 Antibody (8E719) can be used in WB,IP,IF. |
| Alias | PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:10-200; IHC: 1:10-200; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Cells selected for resistance to a single cytotoxic drug may become cross-resistant to a broad range of drugs with different structures and cellular targets. This phenomenon is called multiple drug resistance (MDR). The MDR proteins (Mdrs) are members of a highly conserved superfamily of ATP-binding cassette transport proteins. Mdr functions as an energy-dependent efflux pump for structurally diverse agents ranging from ions to peptides. It is implicated in the development of the multiple drug resistance observed in human cancer cells following prolonged chemotherapy. The classic form of MDR is associated with an increase in the Mdr protein, but not all cases of MDR can be attributed to a rise in Mdr levels. Mdr-1 is an apical transmembrane protein that is an integral part of the blood-brain barrier and functions as a drug-transport pump transporting a variety of drugs from the brain back into the blood. In the human population, there are 15 polymorphisms in the Mdr-1 gene. |
| Conjucates | Unconjugated |
| Immunogen | Mdr of hamster origin |
| Uniprot ID |
| Molecular Weight | Theoretical: 170 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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