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Clopidogrel hydrogen sulfate

Name: Clopidogrel hydrogen sulfate
Brand: TargetMol
SKU: T0182L
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0182LCas No. 120202-66-6

Alias SR-25990C, (S)-(+)-Clopidogrel hydrogen sulfate, (S)-(+)-Clopidogrel bisulfate

Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation.

Clopidogrel hydrogen sulfate

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Purity: 99.79%

Catalog No. T0182LAlias SR-25990C, (S)-(+)-Clopidogrel hydrogen sulfate, (S)-(+)-Clopidogrel bisulfateCas No. 120202-66-6

Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$30	In Stock	In Stock
50 mg	$40	In Stock	In Stock
100 mg	$50	In Stock	In Stock
200 mg	$58	In Stock	In Stock
500 mg	$81	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.79%

Color:White to Yellow

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation.
Targets&IC50	CYP2B6:18.2 nM (IC50), CYP2C19:524 nM (IC50)
In vitro	In a rat model of ulcer margins, daily administration of Clopidogrel (2 mg and 10 mg/kg) significantly reduced the proliferation of gastric epithelial cells induced by ulcers, as well as the expression of the EGF receptor and phosphorylated extracellular signal-regulated kinase. In rats with congestive heart failure, Clopidogrel enhanced the phosphorylation of AKT and eNOS, thereby improving vascular endothelial function and the bioavailability of nitric oxide.
In vivo	In RGM-1 cells, Clopidogrel (1 μM) inhibits the epidermal growth factor-induced activation of epidermal growth factor receptor, PERK expression, and cellular proliferation.
Synonyms	SR-25990C, (S)-(+)-Clopidogrel hydrogen sulfate, (S)-(+)-Clopidogrel bisulfate

Chemical Properties

Molecular Weight	419.9
Formula	C₁₆H₁₆ClNO₂S·H₂SO₄
Cas No.	120202-66-6
Smiles	OS(O)(=O)=O.COC(=O)[C@@H](N1CCc2sccc2C1)c1ccccc1Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (595.38 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3815 mL	11.9076 mL	23.8152 mL	119.0760 mL
5 mM	0.4763 mL	2.3815 mL	4.7630 mL	23.8152 mL
10 mM	0.2382 mL	1.1908 mL	2.3815 mL	11.9076 mL
20 mM	0.1191 mL	0.5954 mL	1.1908 mL	5.9538 mL
50 mM	0.0476 mL	0.2382 mL	0.4763 mL	2.3815 mL
100 mM	0.0238 mL	0.1191 mL	0.2382 mL	1.1908 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc