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Clopidogrel hydrogen sulfate

Name: Clopidogrel hydrogen sulfate
Brand: TargetMol
SKU: T0182L
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T0182LCas No. 120202-66-6

Alias SR-25990C, (S)-(+)-Clopidogrel hydrogen sulfate, (S)-(+)-Clopidogrel bisulfate

Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation.

Clopidogrel hydrogen sulfate

🥰Excellent

Purity: 99.79%

Catalog No. T0182LAlias SR-25990C, (S)-(+)-Clopidogrel hydrogen sulfate, (S)-(+)-Clopidogrel bisulfateCas No. 120202-66-6

Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation.

Pack Size	Price	Availability
25 mg	$30	In Stock
50 mg	$40	In Stock
100 mg	$50	In Stock
200 mg	$58	In Stock
500 mg	$81	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Purity:99.79%

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation.
Targets&IC50	CYP2B6:18.2 nM (IC50), CYP2C19:524 nM (IC50)
In vitro	In a rat model of ulcer margins, daily administration of Clopidogrel (2 mg and 10 mg/kg) significantly reduced the proliferation of gastric epithelial cells induced by ulcers, as well as the expression of the EGF receptor and phosphorylated extracellular signal-regulated kinase. In rats with congestive heart failure, Clopidogrel enhanced the phosphorylation of AKT and eNOS, thereby improving vascular endothelial function and the bioavailability of nitric oxide.
In vivo	In RGM-1 cells, Clopidogrel (1 μM) inhibits the epidermal growth factor-induced activation of epidermal growth factor receptor, PERK expression, and cellular proliferation.
Synonyms	SR-25990C, (S)-(+)-Clopidogrel hydrogen sulfate, (S)-(+)-Clopidogrel bisulfate

Chemical Properties

Molecular Weight	419.9
Formula	C₁₆H₁₆ClNO₂S·H₂SO₄
Cas No.	120202-66-6
Smiles	OS(O)(=O)=O.COC(=O)[C@@H](N1CCc2sccc2C1)c1ccccc1Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (130.98 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3815 mL	11.9076 mL	23.8152 mL	119.0760 mL
5 mM	0.4763 mL	2.3815 mL	4.7630 mL	23.8152 mL
10 mM	0.2382 mL	1.1908 mL	2.3815 mL	11.9076 mL
20 mM	0.1191 mL	0.5954 mL	1.1908 mL	5.9538 mL
50 mM	0.0476 mL	0.2382 mL	0.4763 mL	2.3815 mL
100 mM	0.0238 mL	0.1191 mL	0.2382 mL	1.1908 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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