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TargetMol | Compound Library

PPI Inhibitor Library

Catalog No. L9400

Protein-protein interaction (PPI) inhibitors represent a vast class of therapeutic targets both intracellularly and extracellularly for a broad range of diseases, for instance cancer and HIV. The human interactome has been estimated to cover ~400,000 protein–protein interactions, making PPIs central to many biological processes, including enzymatic activity, assembly of protein complexes and subcellular localisation. However, PPIs are considered difficult to target. As a part of disease biological processes are often dysregulated, therefore PPIs have become an attractive target for therapy. TargetMol's PPI Inhibitor Library, a focused collection of 485 PPI-related compounds, can be used for research on protein-protein interaction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9400

PPI Inhibitor Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 485 PPI-related compounds for drug screening;
  • Targets include PD-1/PD-L1, Bcl-2, BET bromodomain, BRD4 bromodomain, etc.
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Epigenetic Reader Domain
Apoptosis
Bcl-2 Family
MDM-2/p53
Autophagy
Nrf2
HIV Protease
p53
E1/E2/E3 Enzyme
Mdm2
Ras
PD-1/PD-L1
Histone Methyltransferase
Caspase
NF-κB
IAP
Endogenous Metabolite
PROTACs
Ferroptosis
Histone Acetyltransferase
Wnt/beta-catenin
RIP kinase
DNA/RNA Synthesis
Antibacterial
TNF
Microtubule Associated
PARP
p38 MAPK
Sirtuin
Bcl-6
COX
c-Myc
ERK
Akt
Parasite
STAT
Ligands for Target Protein for PROTAC
IL Receptor
HIF/HIF Prolyl-Hydroxylase
Rho
Reactive Oxygen Species
CDK
PI3K
Dehydrogenase
YAP
Raf
MAPK
Integrin
JNK
PERK
Virus Protease
iGluR
mTOR
IFNAR
PKC
Molecular Glues
Antifungal
PPAR
NMDAR
Potassium Channel
Estrogen/progestogen Receptor
HIF
Sodium Channel
Antibiotic
Mitophagy
Calcium Channel
HSP
Ligand for E3 Ligase
PDE
Src
NEDD8
Antioxidant
HDAC
NADPH
5-HT Receptor
Anti-infection
MicroRNA
VEGFR
PLK
Dopamine Receptor
Influenza Virus
GTPase
Lipoxygenase
Carboxypeptidase
Reverse Transcriptase
GABA Receptor
DNA-PK
GSK-3
Estrogen Receptor/ERR
Integrase
JAK
Interleukin
IκB/IKK
Proton pump
DNA Alkylator/Crosslinker
Phosphatase
Aryl Hydrocarbon Receptor
CXCR
P-gp
TLR
Kras
PGK1
ATPase
HBV
ATG
Monoamine Transporter
CCR
Cholinesterase (ChE)
GluR
IGF-1R
DNA
Necroptosis
Arp2/3 Complex
Stearoyl-CoA Desaturase (SCD)
Cytochromes P450
PSMA
Antiviral
transporter
HuR
Beta Amyloid
PDK
DNA Methyltransferase
Thrombin
AhR
Serine Protease
Glucokinase
Immunology/Inflammation related
Gamma-secretase
Mitochondrial Metabolism
ROS
Target Protein Ligand-Linker Conjugate
MNK
OAT
GPCR19
PI4K
Neurotensin Receptor
UGT
Bcr-Abl
Androgen Receptor
Discoidin Domain Receptor (DDR)
HMG-CoA Reductase
FAK
DYRK
Liver X Receptor
EGFR
Ephrin Receptor
GST
NPC1L1
Reductase
Histamine Receptor
Serotonin Transporter
Myosin
Smo
Hedgehog/Smoothened
TGF-beta/Smad
Beta-Secretase
SARS-CoV
Neurokinin receptor
Chloride channel
HCV Protease
MyD88
Glutathione Peroxidase
Serine/threonin kinase
Cysteine Protease
FXR
Topoisomerase
Prostaglandin Receptor
STING
FKBP
Retinoid Receptor
ATTECs
Tyrosinase
MLK
NO Synthase

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