Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
TargetMol | Compound Library

PPI Inhibitor Library

Catalog No. L9400

Protein-protein interaction (PPI) inhibitors represent a vast class of therapeutic targets both intracellularly and extracellularly for a broad range of diseases, for instance cancer and HIV. The human interactome has been estimated to cover ~400,000 protein–protein interactions, making PPIs central to many biological processes, including enzymatic activity, assembly of protein complexes and subcellular localisation. However, PPIs are considered difficult to target. As a part of disease biological processes are often dysregulated, therefore PPIs have become an attractive target for therapy.

TargetMol's PPI Inhibitor Library, a focused collection of 485 PPI-related compounds, can be used for research on protein-protein interaction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Resource Download
Library compound info
Excel
SDF
Contact us for more batch information

Catalog No. L9400

PPI Inhibitor Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
Inquiry & Custom

Top Publication Citing
Use of TargetMol Products

Cite scientific literature on TargetMol products

View More

Product Description Product Description

  • A unique collection of 485 PPI-related compounds for drug screening;
  • Targets include PD-1/PD-L1, Bcl-2, BET bromodomain, BRD4 bromodomain, etc.
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
Inquiry & Custom

Library Customization | TargetMol Library Composition

Epigenetic Reader Domain
Apoptosis
Bcl-2 Family
MDM-2/p53
Autophagy
Nrf2
HIV Protease
E1/E2/E3 Enzyme
p53
Mdm2
Ras
PD-1/PD-L1
Caspase
NF-κB
Histone Methyltransferase
PROTACs
IAP
Histone Acetyltransferase
Endogenous Metabolite
DNA/RNA Synthesis
Ferroptosis
TNF
RIP kinase
Wnt/beta-catenin
p38 MAPK
Akt
PARP
Antibacterial
Microtubule Associated
HIF/HIF Prolyl-Hydroxylase
c-Myc
Bcl-6
ROS
Rho
ERK
Reactive Oxygen Species
Parasite
COX
STAT
Virus Protease
Sirtuin
CDK
Ligands for Target Protein for PROTAC
IL Receptor
MAPK
YAP
Dehydrogenase
Raf
Molecular Glues
PERK
mTOR
Integrin
JNK
JAK
Interleukin
SARS-CoV
PPAR
PI3K
HIF
Sodium Channel
IFNAR
PKC
iGluR
Calcium Channel
HSP
Estrogen/progestogen Receptor
NMDAR
Potassium Channel
PDE
TLR
GTPase
Liver X Receptor
Carboxypeptidase
Reverse Transcriptase
GABA Receptor
Antibiotic
Beta Amyloid
5-HT Receptor
Anti-infection
Src
NEDD8
Antioxidant
Cholinesterase (ChE)
IGF-1R
HDAC
DNA-PK
Reductase
Mitophagy
GSK-3
Estrogen Receptor/ERR
Integrase
IκB/IKK
Dopamine Receptor
Ligands for E3 Ligase
Influenza Virus
MicroRNA
Antifungal
VEGFR
Gamma-secretase
PLK
Proton pump
DNA Alkylator/Crosslinker
Arrestin
Phosphatase
Aryl Hydrocarbon Receptor
CXCR
P-gp
KRas
PGK1
DYRK
MAO
Lipoxygenase
EGFR
Ephrin Receptor
GST
NOD
NADPH
Necroptosis
Pim
Arp2/3 Complex
Stearoyl-CoA Desaturase (SCD)
Cytochromes P450
CaMK
PSMA
Antiviral
transporter
HuR
DNA Methyltransferase
Thrombin
AhR
Monoamine Oxidase
ATPase
HBV
ATG
Target Protein Ligand-Linker Conjugates
Monoamine Transporter
CCR
GluR
DNA
NPC1L1
RAAS
Histamine Receptor
Serotonin Transporter
Myosin
Smo
Hedgehog/Smoothened
TGF-beta/Smad
Beta-Secretase
Neurokinin receptor
Neurotensin Receptor
Adenylate cyclase
UGT
Bcr-Abl
Androgen Receptor
Discoidin Domain Receptor (DDR)
HMG-CoA Reductase
FAK
Glucokinase
Immunology/Inflammation related
Mitochondrial Metabolism
Chk
OAT
MNK
Trk receptor
GPCR19
PI4K
Chloride channel
HCV Protease
MyD88
Glutathione Peroxidase
Cysteine Protease
FXR
Prostaglandin Receptor
STING
FKBP
Retinoid Receptor
Tyrosinase
MLK
NO Synthase

Keywords