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TargetMol | Compound Library

PPI Inhibitor Library

Catalog No. L9400

Protein-protein interaction (PPI) inhibitors represent a vast class of therapeutic targets both intracellularly and extracellularly for a broad range of diseases, for instance cancer and HIV. The human interactome has been estimated to cover ~400,000 protein–protein interactions, making PPIs central to many biological processes, including enzymatic activity, assembly of protein complexes and subcellular localisation. However, PPIs are considered difficult to target. As a part of disease biological processes are often dysregulated, therefore PPIs have become an attractive target for therapy.

TargetMol's PPI Inhibitor Library, a focused collection of 485 PPI-related compounds, can be used for research on protein-protein interaction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9400

PPI Inhibitor Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 485 PPI-related compounds for drug screening;
  • Targets include PD-1/PD-L1, Bcl-2, BET bromodomain, BRD4 bromodomain, etc.
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Epigenetic Reader Domain
Apoptosis
Bcl-2 Family
MDM-2/p53
Autophagy
Nrf2
HIV Protease
p53
E1/E2/E3 Enzyme
Mdm2
Ras
PD-1/PD-L1
Histone Methyltransferase
Caspase
NF-κB
Endogenous Metabolite
PROTACs
IAP
Ferroptosis
Histone Acetyltransferase
Wnt/beta-catenin
RIP kinase
Antibacterial
DNA/RNA Synthesis
TNF
p38 MAPK
PARP
Akt
Microtubule Associated
c-Myc
Bcl-6
ERK
COX
Sirtuin
HIF/HIF Prolyl-Hydroxylase
Ligands for Target Protein for PROTAC
PI3K
Parasite
Rho
CDK
Reactive Oxygen Species
IL Receptor
STAT
Integrin
Dehydrogenase
YAP
PERK
JNK
PPAR
PKC
Raf
MAPK
Estrogen/progestogen Receptor
Antifungal
IFNAR
Mitophagy
Virus Protease
Calcium Channel
iGluR
PDE
NMDAR
Molecular Glues
mTOR
HSP
Ligand for E3 Ligase
HIF
Potassium Channel
Sodium Channel
Antibiotic
Proton pump
MicroRNA
Dopamine Receptor
DNA-PK
Src
NEDD8
Antioxidant
DNA Alkylator/Crosslinker
NADPH
Phosphatase
GTPase
GSK-3
Estrogen Receptor/ERR
VEGFR
Aryl Hydrocarbon Receptor
Integrase
JAK
CXCR
Lipoxygenase
Interleukin
P-gp
TLR
Influenza Virus
IκB/IKK
Carboxypeptidase
Reverse Transcriptase
HDAC
5-HT Receptor
GABA Receptor
PLK
Anti-infection
Kras
PGK1
ATPase
Chloride channel
NPC1L1
HCV Protease
MyD88
Reductase
DYRK
Histamine Receptor
Necroptosis
Glutathione Peroxidase
HBV
Serine Protease
ATG
Serotonin Transporter
Serine/threonin kinase
Cysteine Protease
Liver X Receptor
Neurotensin Receptor
FXR
Glucokinase
Immunology/Inflammation related
Myosin
UGT
Bcr-Abl
Gamma-secretase
Arp2/3 Complex
Mitochondrial Metabolism
Monoamine Transporter
ROS
Smo
Hedgehog/Smoothened
Stearoyl-CoA Desaturase (SCD)
CCR
Cholinesterase (ChE)
GluR
Cytochromes P450
IGF-1R
DNA
Androgen Receptor
TGF-beta/Smad
EGFR
Target Protein Ligand-Linker Conjugate
Beta-Secretase
PSMA
OAT
MNK
Antiviral
Prostaglandin Receptor
SARS-CoV
STING
GPCR19
Ephrin Receptor
transporter
HuR
GST
Beta Amyloid
FKBP
Retinoid Receptor
PI4K
PDK
ATTECs
Discoidin Domain Receptor (DDR)
Neurokinin receptor
DNA Methyltransferase
HMG-CoA Reductase
Tyrosinase
Thrombin
FAK
AhR
MLK
NO Synthase

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