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TargetMol | Compound Library

PPI Inhibitor Library

Catalog No. L9400

Protein-protein interaction (PPI) inhibitors represent a vast class of therapeutic targets both intracellularly and extracellularly for a broad range of diseases, for instance cancer and HIV. The human interactome has been estimated to cover ~400,000 protein–protein interactions, making PPIs central to many biological processes, including enzymatic activity, assembly of protein complexes and subcellular localisation. However, PPIs are considered difficult to target. As a part of disease biological processes are often dysregulated, therefore PPIs have become an attractive target for therapy.

TargetMol's PPI Inhibitor Library, a focused collection of 485 PPI-related compounds, can be used for research on protein-protein interaction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9400

PPI Inhibitor Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 485 PPI-related compounds for drug screening;
  • Targets include PD-1/PD-L1, Bcl-2, BET bromodomain, BRD4 bromodomain, etc.
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Epigenetic Reader Domain
Apoptosis
Bcl-2 Family
MDM-2/p53
Autophagy
Nrf2
HIV Protease
E1/E2/E3 Enzyme
p53
Mdm2
Ras
PD-1/PD-L1
NF-κB
Caspase
Histone Methyltransferase
PROTACs
IAP
DNA/RNA Synthesis
Histone Acetyltransferase
Endogenous Metabolite
Ferroptosis
RIP kinase
Akt
TNF
p38 MAPK
Wnt/beta-catenin
Antibacterial
PARP
Microtubule Associated
HIF/HIF Prolyl-Hydroxylase
c-Myc
Bcl-6
ERK
ROS
COX
Sirtuin
Ligands for Target Protein for PROTAC
PI3K
Virus Protease
Parasite
Rho
CDK
Reactive Oxygen Species
IL Receptor
MAPK
STAT
Integrin
Dehydrogenase
YAP
PERK
JNK
PPAR
Raf
Molecular Glues
Interleukin
SARS-CoV
Estrogen/progestogen Receptor
Antifungal
IFNAR
Mitophagy
VEGFR
Calcium Channel
PKC
iGluR
PDE
NMDAR
Ligands for E3 Ligase
JAK
mTOR
HSP
TLR
HIF
Potassium Channel
Sodium Channel
Antibiotic
Proton pump
MicroRNA
Dopamine Receptor
DNA-PK
Src
NEDD8
Antioxidant
DNA Alkylator/Crosslinker
Reductase
Arrestin
NADPH
Phosphatase
GTPase
GSK-3
Estrogen Receptor/ERR
Liver X Receptor
Aryl Hydrocarbon Receptor
Gamma-secretase
Integrase
CXCR
Cholinesterase (ChE)
Lipoxygenase
IGF-1R
P-gp
Influenza Virus
IκB/IKK
Carboxypeptidase
Reverse Transcriptase
HDAC
5-HT Receptor
GABA Receptor
PLK
Anti-infection
Kras
PGK1
ATPase
Chloride channel
NPC1L1
HCV Protease
MyD88
DYRK
RAAS
Histamine Receptor
Necroptosis
Glutathione Peroxidase
HBV
Pim
ATG
Serotonin Transporter
Target Protein Ligand-Linker Conjugates
Cysteine Protease
Neurotensin Receptor
FXR
Glucokinase
Immunology/Inflammation related
Myosin
UGT
Bcr-Abl
Arp2/3 Complex
Mitochondrial Metabolism
Monoamine Transporter
Smo
Hedgehog/Smoothened
Stearoyl-CoA Desaturase (SCD)
CCR
Chk
GluR
Cytochromes P450
DNA
CaMK
Androgen Receptor
TGF-beta/Smad
EGFR
Beta-Secretase
PSMA
OAT
MNK
Antiviral
Prostaglandin Receptor
STING
Trk receptor
GPCR19
Ephrin Receptor
transporter
HuR
GST
Beta Amyloid
FKBP
Retinoid Receptor
PI4K
PDK
Discoidin Domain Receptor (DDR)
Neurokinin receptor
DNA Methyltransferase
HMG-CoA Reductase
Tyrosinase
Thrombin
FAK
AhR
MLK
NO Synthase

Keywords