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TargetMol | Compound Library

PPI Inhibitor Library

Catalog No. L9400

Protein-protein interaction (PPI) inhibitors represent a vast class of therapeutic targets both intracellularly and extracellularly for a broad range of diseases, for instance cancer and HIV. The human interactome has been estimated to cover ~400,000 protein–protein interactions, making PPIs central to many biological processes, including enzymatic activity, assembly of protein complexes and subcellular localisation. However, PPIs are considered difficult to target. As a part of disease biological processes are often dysregulated, therefore PPIs have become an attractive target for therapy. TargetMol's PPI Inhibitor Library, a focused collection of 485 PPI-related compounds, can be used for research on protein-protein interaction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9400

PPI Inhibitor Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 485 PPI-related compounds for drug screening;
  • Targets include PD-1/PD-L1, Bcl-2, BET bromodomain, BRD4 bromodomain, etc.
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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Epigenetic Reader Domain
Apoptosis
Bcl-2 Family
Autophagy
Nrf2
p53
HIV Protease
Mdm2
E1/E2/E3 Enzyme
Histone Methyltransferase
PD-1/PD-L1
Caspase
IAP
NF-κB
PROTACs
Endogenous Metabolite
Ferroptosis
RIP kinase
DNA/RNA Synthesis
Wnt/beta-catenin
Histone Acetyltransferase
PARP
Microtubule Associated
p38 MAPK
Ras
Antibacterial
c-Myc
COX
Sirtuin
STAT
TNF
Akt
CDK
ERK
Rho
Dehydrogenase
HIF/HIF Prolyl-Hydroxylase
IL Receptor
Integrin
JNK
Ligands for Target Protein for PROTAC
Parasite
Raf
Calcium Channel
CXCR
HIF
HSP
Ligand for E3 Ligase
Mitophagy
mTOR
NMDAR
PERK
PI3K
PKC
PPAR
Reactive Oxygen Species
Sodium Channel
YAP
5-HT Receptor
Antibiotic
Antifungal
Antioxidant
Aryl Hydrocarbon Receptor
Carboxypeptidase
DNA Alkylator/Crosslinker
DNA-PK
Dopamine Receptor
Estrogen/progestogen Receptor
GABA Receptor
GSK-3
GTPase
HDAC
IFNAR
iGluR
Influenza Virus
Integrase
IκB/IKK
JAK
Lipoxygenase
MicroRNA
NEDD8
PDE
P-gp
Phosphatase
PLK
Reverse Transcriptase
Src
Virus Protease
AhR
Androgen Receptor
Anti-infection
Antiviral
ATPase
ATTECs
Beta Amyloid
CCR
Chloride channel
Cholinesterase (ChE)
Cysteine Protease
Cytochromes P450
Discoidin Domain Receptor (DDR)
DNA
DNA Methyltransferase
Ephrin Receptor
Estrogen Receptor/ERR
FAK
FXR
Gamma-secretase
Glucokinase
GluR
Glutathione Peroxidase
GPCR19
HBV
HCV Protease
Hedgehog/Smoothened
Histamine Receptor
HMG-CoA Reductase
HuR
IGF-1R
Interleukin
Liver X Receptor
MAO
MAPK
Mitochondrial Metabolism
MLK
MMP
MNK
Molecular Glues
Monoamine Oxidase
Monoamine Transporter
MyD88
Myosin
NADPH
Neurokinin receptor
Neurotensin Receptor
NO Synthase
NPC1L1
PDK
Potassium Channel
Prostaglandin Receptor
Proton pump
PSMA
Retinoid Receptor
ROS
Serine/threonin kinase
Serotonin Transporter
Smo
STING
TGF-beta/Smad
Thrombin
TLR
Topoisomerase
transporter
Tyrosinase
UGT
VEGFR
Kras