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Nectin-4 Protein, Human, Recombinant (His & Avi), Biotinylated

Catalog No. TMPJ-00310
Synonyms: Nectin-4, PVRL4, LNIR, PRR4, Ig superfamily receptor LNIR, Poliovirus receptor-related protein 4

Nectin-4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 40-50 KDa and the accession number is Q96NY8.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Nectin-4 Protein, Human, Recombinant (His & Avi), Biotinylated
Pack Size Availability Price/USD Quantity
20 μg 5 days $ 355.00
100 μg 5 days $ 963.00
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Biological Description
Technical Params
Product Properties
Description Nectin-4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 40-50 KDa and the accession number is Q96NY8.
Species Human
Expression System HEK293 Cells
Tag C-6xHis-Avi
Accession Number Q96NY8
Synonyms Nectin-4, PVRL4, LNIR, PRR4, Ig superfamily receptor LNIR, Poliovirus receptor-related protein 4
Amino Acid Gly32-Val351
Construction Gly32-Val351
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 40-50 KDa, reducing conditions
Endotoxin < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.

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Keywords

Nectin-4 Protein, Human, Recombinant (His & Avi), Biotinylated Nectin-4 PVRL 4 PVRL4 LNIR PRR4 Ig superfamily receptor LNIR PRR-4 PRR 4 Poliovirus receptor-related protein 4 PVRL-4 recombinant recombinant-proteins proteins protein

 

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