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Anti-PI 3 Kinase p110 delta Antibody (6K824)

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Catalog No. TMAC-03287

Anti-PI 3 Kinase p110 delta Antibody (6K824) is a Rabbit antibody targeting PI 3 Kinase p110 delta. Anti-PI 3 Kinase p110 delta Antibody (6K824) can be used in WB,IHC.

Anti-PI 3 Kinase p110 delta Antibody (6K824)

Anti-PI 3 Kinase p110 delta Antibody (6K824)

😃Good
Catalog No. TMAC-03287
Anti-PI 3 Kinase p110 delta Antibody (6K824) is a Rabbit antibody targeting PI 3 Kinase p110 delta. Anti-PI 3 Kinase p110 delta Antibody (6K824) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-PI 3 Kinase p110 delta Antibody (6K824) is a Rabbit antibody targeting PI 3 Kinase p110 delta. Anti-PI 3 Kinase p110 delta Antibody (6K824) can be used in WB,IHC.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundPhosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110 forms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. It has been shown to bind p85α and β, but it apparently does not phosphorylate these subunits. p110δ has the capacity to autophosphorylate and results in the nearly complete inactivation of the lipid kinase activity. Interestingly, p110γ does not interact with the p85 subunits and has been shown to be activated by α and βγ heterotrimeric G proteins. Two p110δ isoforms have been identified and are widely expressed. Isoform 1 is expressed predominantly in leukocytes while isoform 2 is expressed in normal thymus, lung and spleen tissues.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
49634
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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