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Anti-EPOR Monoclonal Antibody is a humanized rabbit antibody targeting EPOR. Anti-EPOR Monoclonal Antibody can be used in ELISA,FCM,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μg | $288 | 12 days | 12 days | |
| 50 μg | $346 | 12 days | 12 days | |
| 100 μg | $484 | 12 days | 12 days |
| Description | Anti-EPOR Monoclonal Antibody is a humanized rabbit antibody targeting EPOR. Anti-EPOR Monoclonal Antibody can be used in ELISA,FCM,IF. |
| Synonyms | Erythropoietin receptor |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of EPOR overexpressed 371F cells with TMAZ-0026, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of EPOR protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation (PubMed: 10388848, PubMed: 2163695, PubMed: 2163696, PubMed: 8662939, PubMed: 9774108). Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade (By similarity). In some cell types, can also activate STAT1 and STAT3 (PubMed: 11756159). May also activate the LYN tyrosine kinase (By similarity)|Acts as a dominant-negative receptor of EPOR-mediated signaling |
| Conjucates | Unconjugated |
| Others Formats | Biotin |
| Antibody Types Available | 2 |
| Immunogen | EPOR |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology Research |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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