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Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $33 | In Stock | |
| 5 mg | $74 | In Stock | |
| 10 mg | $120 | In Stock | |
| 25 mg | $257 | In Stock | |
| 50 mg | $406 | In Stock | |
| 100 mg | $588 | In Stock | |
| 200 mg | $855 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $82 | In Stock |
| Description | Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses. |
| In vitro | Dehydroepiandrosterone sulfate selectively increases the length of neurites containing the dendritic marker MAP-2 and increases neuronal excitability when directly applied to septal-preoptic neurons[1]. |
| In vivo | Chronic administration of Dehydroepiandrosterone sulfate produces a dose-dependent effect on performance. In male Sprague-Dawley rats, Dehydroepiandrosterone sulfate (5-20 mg/kg; s.c.) is significantly effective in improving latency to reach the platform[3]. |
| Synonyms | Prasterone sulfate, PB-005, PB005, PB 005, DHEAS, DHEA sulfate |
| Molecular Weight | 368.49 |
| Formula | C19H28O5S |
| Cas No. | 651-48-9 |
| Smiles | [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OS(O)(=O)=O |
| Relative Density. | 1.1763 g/cm3 (Estimated) |
| Color | White |
| Appearance | Solid |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 91.8 mg/mL (249.1 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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