Home Tools
Log in
Cart

CCR4 Protein-VLP, Human, Recombinant (His)

Catalog No. TMPH-01065
Synonyms: CC-CKR-4, CCR4, CCR-4, CD194, C-C chemokine receptor type 4, K5-5, CMKBR4, C-C CKR-4

High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CCR4 Protein-VLP, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 530.00
100 μg 20 days $ 1,060.00
500 μg 20 days $ 3,360.00
Bulk Inquiry
Get quote
Contact us for more batch information
Biological Description
Technical Params
Product Properties
Description High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Species Human
Expression System HEK293
Tag C-terminal 10xHis-tagged (This tag can be tested only under denaturing conditions)
Accession Number P51679
Synonyms CC-CKR-4, CCR4, CCR-4, CD194, C-C chemokine receptor type 4, K5-5, CMKBR4, C-C CKR-4
Amino Acid MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTCYTERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLHDAL
Construction 1-360 aa
Molecular Weight 43.2 kDa (predicted)
Endotoxin < 1.0 EU per μg protein as determined by the LAL method.
Formulation PBS, pH 7.4, 6% trehalose
Reconstitution A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

Calculator

Reconstitution Calculator
Recombinant Proteins Dilute Calculator
Specific Activity Calculator
=
÷
X
=
X
(Unit/mg)
= 106 ÷
ng/mL

bottom

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

CCR4 Protein-VLP, Human, Recombinant (His) CC-CKR-4 CCR4 CCR-4 CD194 C-C chemokine receptor type 4 K5-5 CMKBR4 C-C CKR-4 recombinant recombinant-proteins proteins protein

 

TargetMol