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α-Casozepine

Name: α-Casozepine
Brand: TargetMol
SKU: T29892
Price: 44 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T29892Cas No. 117592-45-7

Alias Lactium, alpha-Casozepine

α-Casozepine, a bioactive peptide derived from milk α-S1 casein, exhibits affinity for γ-aminobutyric acid (GABA) receptors in the brain and demonstrates anti-anxiety effects.

α-Casozepine

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Purity: 99.81%

Catalog No. T29892Alias Lactium, alpha-CasozepineCas No. 117592-45-7

α-Casozepine, a bioactive peptide derived from milk α-S1 casein, exhibits affinity for γ-aminobutyric acid (GABA) receptors in the brain and demonstrates anti-anxiety effects.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$44	-	In Stock
5 mg	$89	-	In Stock
10 mg	$143	-	In Stock
25 mg	$289	-	In Stock
50 mg	$463	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.81%

Appearance:Solid

Color:White

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Product Introduction

Bioactivity

Description	α-Casozepine, a bioactive peptide derived from milk α-S1 casein, exhibits affinity for γ-aminobutyric acid (GABA) receptors in the brain and demonstrates anti-anxiety effects.
Synonyms	Lactium, alpha-Casozepine

Chemical Properties

Molecular Weight	1267.47
Formula	C₆₀H₉₄N₁₄O₁₆
Cas No.	117592-45-7
Smiles	[C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CC(C)C)=O)CC(C)C)=O)CCC(N)=O)=O)CCC(O)=O)=O)CC(C)C)=O)NC(CNC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)CC(C)C)=O)=O
Relative Density.	1.37 g/cm3 (Predicted)
Sequence	Tyr-Leu-Gly-Tyr-Leu-Glu-Gln-Leu-Leu-Arg
Sequence Short	YLGYLEQLLR

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 15 mg/mL (11.83 mM), Sonication is recommended.

H2O: 50 mg/mL (39.45 mM), when pH is adjusted to 2 with 1 M HCl. Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	0.7890 mL	3.9449 mL	7.8897 mL	39.4487 mL
5 mM	0.1578 mL	0.7890 mL	1.5779 mL	7.8897 mL
10 mM	0.0789 mL	0.3945 mL	0.7890 mL	3.9449 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.0394 mL	0.1972 mL	0.3945 mL	1.9724 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc