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TC-O 9311

🥰Excellent
Catalog No. T4626LCas No. 444932-31-4
Alias TCO-9311, TC-O-9311, TC-O9311, TCO9311, TC-O 9311, TCO 9311

TC-O 9311 (TCO-9311) is an effective agonist of GPR139 (EC50 = 39 nM in CHO-K1 cells expressing human GPR139).

TC-O 9311

TC-O 9311

🥰Excellent
Purity: 99.84%
Catalog No. T4626LAlias TCO-9311, TC-O-9311, TC-O9311, TCO9311, TC-O 9311, TCO 9311Cas No. 444932-31-4
TC-O 9311 (TCO-9311) is an effective agonist of GPR139 (EC50 = 39 nM in CHO-K1 cells expressing human GPR139).
Pack SizePriceAvailabilityQuantity
5 mg$30In Stock
10 mg$48In Stock
25 mg$95In Stock
50 mg$153In Stock
100 mg$248In Stock
200 mg$353In Stock
1 mL x 10 mM (in DMSO)$32In Stock
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Batch Information

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Purity:99.84%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
TC-O 9311 (TCO-9311) is an effective agonist of GPR139 (EC50 = 39 nM in CHO-K1 cells expressing human GPR139).
Targets&IC50
GPR139:EC50 = 39 nM (in CHO-K1 cells)
SynonymsTCO-9311, TC-O-9311, TC-O9311, TCO9311, TC-O 9311, TCO 9311
Chemical Properties
Molecular Weight365.38
FormulaC20H19N3O4
Cas No.444932-31-4
SmilesCOc1cc(OC)cc(c1)C(=O)NNC(=O)Nc1cccc2ccccc12
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 125 mg/mL (342.11 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (10.95 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7369 mL13.6844 mL27.3688 mL136.8438 mL
5 mM0.5474 mL2.7369 mL5.4738 mL27.3688 mL
10 mM0.2737 mL1.3684 mL2.7369 mL13.6844 mL
20 mM0.1368 mL0.6842 mL1.3684 mL6.8422 mL
50 mM0.0547 mL0.2737 mL0.5474 mL2.7369 mL
100 mM0.0274 mL0.1368 mL0.2737 mL1.3684 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TC O 9311GPR139
Related Tags: buy TC-O 9311 | purchase TC-O 9311 | TC-O 9311 cost | order TC-O 9311 | TC-O 9311 chemical structure | TC-O 9311 formula | TC-O 9311 molecular weight
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