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Anti-Phospho-Paxillin (Tyr118) Antibody (8M93)
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Catalog No. TMAY-01688
Alias p-Paxillin (Y118), p-Paxillin (Tyr118), Phospho-Paxillin (Y118), Paxillin (p-Y118), Paxillin (p-Tyr118)
Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) is a Rabbit antibody targeting Phospho-Paxillin (Tyr118). Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) can be used in WB.
Anti-Phospho-Paxillin (Tyr118) Antibody (8M93)
Anti-Phospho-Paxillin (Tyr118) Antibody (8M93)
😃Good
Catalog No. TMAY-01688Alias p-Paxillin (Y118), p-Paxillin (Tyr118), Phospho-Paxillin (Y118), Paxillin (p-Y118), Paxillin (p-Tyr118)
Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) is a Rabbit antibody targeting Phospho-Paxillin (Tyr118). Anti-Phospho-Paxillin (Tyr118) Antibody (8M93) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $80 | 7-10 days | |
| 100 μL | $234 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: WB Reactivity: Human |
| Alias | p-Paxillin (Y118), p-Paxillin (Tyr118), Phospho-Paxillin (Y118), Paxillin (p-Y118), Paxillin (p-Tyr118) |
| Ig Type | Rabbit IgG |
| Clone | 8M93 |
| Reactivity | Human;
Predicted to React with:Species predicted to react based on 100% sequence homology: Cyomolgus |
| Verified Activity | 1. Western blot analysis of extracts from A-431, untreated (line A); treated with antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-Paxillin (Tyr118) Antibody, Rabbit MAb at 1:1000 dilution. 2. Western blot analysis of extracts from A-431 using Phospho-Paxillin (Tyr118) rabbit monoclonal Antibody at dilution of 1:2000, 1:10000 and 1:50000. |
| Application | WB |
| Recommended Dose | WB: 1:1000-1:5000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around Tyr118 of the Human Phospho-Paxillin. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| Research Background | PXN was significantly upregulated in cervical cancer, which associated with tumor stage, poor differentiation, lymphovascular space invasion and lymphatic metastasis. Knockdown of PXN notably impaired cellular growth and colony formation by suppressing Bcl-2 and inducing marked apoptosis. Moreover, PXN led to resistance to radiation, and downregulation of PXN resensitized C33A cells to radiation.PXN was frequently upregulated and acted as an oncogene via regulating Bcl-2 in cervical cancer, which supports PXN as a potent therapeutic target. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: residues around Tyr118 of the Human Phospho-Paxillin |
| Antigen Species | Human |
| Biology Area | Adaptor Proteins |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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