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SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His)

(Synonyms: UNQ2502/PRO5990, SGIII, Secretogranin-3, Secretogranin III, SCG3) Copy Product Info

Synonyms: UNQ2502/PRO5990, SGIII, Secretogranin-3, Secretogranin III, SCG3

Catalog No. TMPK-01122 Copy Product Info
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs. SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 52.1 kDa and the accession number is Q8WXD2-1.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$517-10 days7-10 days
10 µg$807-10 days7-10 days
20 µg$1297-10 days7-10 days
50 µg$2487-10 days7-10 days
100 µg$4187-10 days7-10 days
200 µg$7577-10 days7-10 days
500 µg$1,6707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Human SG3, His Tag at 0.2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-SG3 Antibody, hFc Tag with the EC50 of 20.6ng/ml determined by ELISA.
Description
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs. SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 52.1 kDa and the accession number is Q8WXD2-1.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberQ8WXD2-1
ConstructionPhe20-Leu468
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsUNQ2502/PRO5990, SGIII, Secretogranin-3, Secretogranin III, SCG3
Research Background
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs.
Chemical Properties
Molecular Weight52.1 kDa (predicted). Due to glycosylation, the protein migrates to 55-68 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His) chemical structure | SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His) molecular weight