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Anti-CD74 Antibody-PE (3H62)
🥰Excellent
Catalog No. TMAY-01630P
Anti-CD74 Antibody-PE (3H62) is a PE-conjugated Mouse antibody targeting CD74. Anti-CD74 Antibody-PE (3H62) can be used in FCM.
Anti-CD74 Antibody-PE (3H62)
Anti-CD74 Antibody-PE (3H62)
🥰Excellent
Catalog No. TMAY-01630P
Anti-CD74 Antibody-PE (3H62) is a PE-conjugated Mouse antibody targeting CD74. Anti-CD74 Antibody-PE (3H62) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD74 Antibody-PE (3H62) is a PE-conjugated Mouse antibody targeting CD74. Anti-CD74 Antibody-PE (3H62) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 3H62 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD74 expression on human peripheral blood lymphocytes. Cells were stained with PE-conjugated anti-Human CD74 and APC-conjugated anti-Human CD19 (BD Pharmingen™ Cat. No. 555415). The dot plots were derived from events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD74 (rh CD74; TMPY-01199; NP_004346.1; Gln73-Met232) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD74, also known as HLA class2 histocompatibility antigen gamma chain and HLA-DR antigens-associated invariant chain, is a polypeptide involved in the formation and transport of MHC class2 protein. CD74 is expressed by B cells, macrophages, and Reed-Sternberg cells. When MHC class 2 protein was in the rough ER, its peptide-binding cleft was blocked by CD74 to prevent it from interacting with the endogenous peptides. CD74 also serves to facilitate MHC class2's export from ER. |
| Conjucates | PE |
| Others Formats | Unconjugated/APC |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Human CD74 protein (TMPY-01199) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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