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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $970 | Backorder |
Description | Odatroltide is a nanoscale P-selectin inhibitor that serves as a nano-delivery system for 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to specifically target the thrombus. |
In vitro | Odatroltide (1 nM) proficiently diminishes P-selectin expression, paralleled by its ability to inhibit platelet aggregation - an effect also seen with DHDMIQK(KAP) through similar down-regulation of P-selectin. Furthermore, Odatroltide impedes platelet clumping triggered by TH, AA, ADP, and PAF, attributing its efficacy to P-selectin downregulation and free radical scavenging[1]. |
In vivo | Odatroltide (0.01 nmol/kg) lyses the thrombus and inhibits thrombosis with a minimal[1]. |
Alias | DHDMIQK(KAP), Odatroltide |
Molecular Weight | 661.801 |
Formula | C32H51N7O8 |
Cas No. | 1639303-73-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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