Home Tools
Log in
Cart

SNCA Protein, Human, Recombinant (His)

Catalog No. TMPJ-00023
Synonyms: α-Synuclein, Alpha-Synuclein, PARK1, Non-A β Component of AD Amyloid, SNCA, Non-A4 Component of Amyloid Precursor, NACP, Non-A Beta Component of AD Amyloid

Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
SNCA Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 60.00
50 μg 5 days $ 129.00
500 μg 5 days $ 806.00
1 mg 5 days $ 1,630.00
Bulk Inquiry
Get quote
Select Batch  
Contact us for more batch information
Biological Description
Technical Params
Product Properties
Description Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).
Species Human
Expression System E. coli
Tag N-6His
Accession Number P37840
Synonyms α-Synuclein, Alpha-Synuclein, PARK1, Non-A β Component of AD Amyloid, SNCA, Non-A4 Component of Amyloid Precursor, NACP, Non-A Beta Component of AD Amyloid
Amino Acid Met1-Ala140
Construction Recombinant Human Alpha-Synuclein is produced by our E.coli expression system and the target gene encoding Met1-Ala140 is expressed with a 6His tag at the N-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 18 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).

Calculator

Reconstitution Calculator
Recombinant Proteins Dilute Calculator
Specific Activity Calculator
=
÷
X
=
X
(Unit/mg)
= 106 ÷
ng/mL

bottom

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

SNCA Protein, Human, Recombinant (His) α-Synuclein PARK 1 Non-A b Component of AD Amyloid Alpha-Synuclein a-Synuclein PARK1 Non-A β Component of AD Amyloid SNCA PARK-1 Non-A4 Component of Amyloid Precursor NACP Non-A Beta Component of AD Amyloid recombinant recombinant-proteins proteins protein

 

TargetMol