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Anti-ITGB1 Antibody-APC (2Z549) is a APC-conjugated Mouse antibody targeting ITGB1. Anti-ITGB1 Antibody-APC (2Z549) can be used in FCM.
Description | Anti-ITGB1 Antibody-APC (2Z549) is a APC-conjugated Mouse antibody targeting ITGB1. Anti-ITGB1 Antibody-APC (2Z549) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 2Z549 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human ITGB1(CD29) expression on human whole blood lymphocytes. Cells were stained with APC-conjugated anti-Human ITGB1(CD29). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
Application | FCM |
Recommended Dose | 5 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Integrin beta 1/ITGB1 (rh Integrin beta 1/ITGB1; TMPY-00476; CAA30790.1; Met1-Asp728) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct target of miR-493-5p suggesting that ITGB1 and miR-493-5p may have potential prognostic value and may be useful as tumor biomarkers for the diagnosis of NSCLC patients. Diseases associated with ITGB1 include Gallbladder Cancer and Breast Cancer. |
Conjucates | APC |
Others Formats | Unconjugated/FITC/PE |
Antibody Types Available | 4 |
Immunogen | Recombinant Human Integrin beta 1/ITGB1 Protein (TMPY-00476) |
Antigen Species | Human |
Biology Area | Cardiac Stem Cell Markers |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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