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Anti-nNOS Polyclonal Antibody
(Synonyms: Peptidyl-cysteine S-nitrosylase NOS1, NOS1, NOS type I, nNOS), N-NOS, Nitric oxide synthase, brain, Neuronal NOS(N-NOS, neuronal Nitric Oxide Synthase, NC-NOS, EC:1.14.13.39, Constitutive NOS, bNOS) Copy Product Info
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Synonyms: Peptidyl-cysteine S-nitrosylase NOS1, NOS1, NOS type I, nNOS), N-NOS, Nitric oxide synthase, brain, Neuronal NOS(N-NOS, neuronal Nitric Oxide Synthase, NC-NOS, EC:1.14.13.39, Constitutive NOS, bNOS
Catalog No. TMAB-01250 Copy Product Info
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Anti-nNOS Polyclonal Antibody is a Rabbit antibody targeting Cellubrevin. Anti-nNOS Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-nNOS Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-nNOS Polyclonal Antibody is a Rabbit antibody targeting Cellubrevin. Anti-nNOS Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Peptidyl-cysteine S-nitrosylase NOS1, NOS1, NOS type I, nNOS), N-NOS, Nitric oxide synthase, brain, Neuronal NOS(N-NOS, neuronal Nitric Oxide Synthase, NC-NOS, EC:1.14.13.39, Constitutive NOS, bNOS |
| Ig Type | IgG |
| Reactivity | Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane, sarcolemma; Peripheral membrane protein. Cell projection, dendritic spine. Note=In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines (By similarity). |
| Tissue Specificity | Isoform 1 is ubiquitously expressed: detected in skeletal muscle and brain, also in testis, lung and kidney, and at low levels in heart, adrenal gland and retina. Not detected in the platelets. Isoform 3 is expressed only in testis. Isoform 4 is detected |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]. |
| Immunogen | KLH conjugated synthetic peptide: human nNos/NOS-1 |
| Antigen Species | Human |
| Gene Name | NOS1 |
| Gene ID | |
| Protein Name | Nitric oxide synthase, brain |
| Uniprot ID | |
| Biology Area | Germ cell markers,Regulation,Embryonic Germ Cells |
| Function | Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. |
| Molecular Weight | Theoretical: 130 kDa. Actual: 150 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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