IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated

IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1.

Pack Size	Availability	Price/USD
100 μg	5 days	$ 814.00
500 μg	5 days	$ 3,250.00
1 mg	5 days	$ 5,440.00

Pack Size

Availability

Price/USD

Quantity

100 μg

5 days

$ 814.00

500 μg

5 days

$ 3,250.00

1 mg

5 days

$ 5,440.00

Description

IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1.

Species	Mouse
Expression System	HEK293 Cells
Tag	C-His-Avi
Accession Number	Q62386-1
Synonyms	IL17A, interleukin 17A, IL17, CTLA-8, IL-17CTLA-8
Construction	Ala26-Ala158
Protein Purity	> 95% as determined by Tris-Bis PAGE
Molecular Weight	18 kDa (predicted). Due to glycosylation, the protein migrates to 19-29 kDa based on Tris-Bis PAGE result.

Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.