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Bisoprolol hemifumarate

🥰Excellent
Catalog No. T0143Cas No. 104344-23-2
Alias EMD33512, Bisoprolol hemifumarate salt, (±)-Bisoprolol hemifumarate, (±)-Bisoprolol (hemifumarate)

Bisoprolol, a selective beta-1 adrenergic receptor antagonist, selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby with antihypertensive activity and devoid of intrinsic sympathomimetic activity.

Bisoprolol hemifumarate
Other Forms of Bisoprolol hemifumarate:

Bisoprolol hemifumarate

🥰Excellent
Purity: 99.84%
Catalog No. T0143Alias EMD33512, Bisoprolol hemifumarate salt, (±)-Bisoprolol hemifumarate, (±)-Bisoprolol (hemifumarate)Cas No. 104344-23-2
Bisoprolol, a selective beta-1 adrenergic receptor antagonist, selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby with antihypertensive activity and devoid of intrinsic sympathomimetic activity.
Pack SizePriceAvailabilityQuantity
50 mg$30In Stock
1 mL x 10 mM (in DMSO)$32In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:99.84%
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COA LCMS HPLC HNMR

Product Introduction

Bioactivity
Description
Bisoprolol, a selective beta-1 adrenergic receptor antagonist, selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby with antihypertensive activity and devoid of intrinsic sympathomimetic activity.
SynonymsEMD33512, Bisoprolol hemifumarate salt, (±)-Bisoprolol hemifumarate, (±)-Bisoprolol (hemifumarate)
Chemical Properties
Molecular Weight383.49
FormulaC20H33NO6
Cas No.104344-23-2
SmilesOC(=O)/C=C/C(=O)O.CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1.CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1
Relative Density.1.033 g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 199.3 mM, Sonication is recommended.
H2O: 26.08 mM, Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.6076 mL13.0381 mL26.0763 mL130.3815 mL
5 mM0.5215 mL2.6076 mL5.2153 mL26.0763 mL
10 mM0.2608 mL1.3038 mL2.6076 mL13.0381 mL
20 mM0.1304 mL0.6519 mL1.3038 mL6.5191 mL
DMSO
1mg5mg10mg50mg
50 mM0.0522 mL0.2608 mL0.5215 mL2.6076 mL
100 mM0.0261 mL0.1304 mL0.2608 mL1.3038 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

β1-adrenergic receptorSK channelmyocardial toxicityhypoxiaH9c2DC cellBisoprolol hemifumarateBisoprololAdrenergicReceptorAdrenergic Receptor
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